MLH3
mutL homolog 3
Synonimy:
HNPCC7
Gatunek:
Human MLH3 (27030), Mouse Mlh3 (217716), Rat Mlh3 (314320), Domestic Rabbit MLH3 (100339094), sheep MLH3 (101109183), dog MLH3 (480389), domestic guinea pig Mlh3 (100735009), domestic cat MLH3 (101096575), Thale Cress MLH3 (829704), Zebrafish mlh3 (568323) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(27030) Summary: This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The protein encoded by this gene functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008]
- Mouse(217716) mutL homolog 3 (E coli)
- Rat(314320) mutL homolog 3 (E. coli)
- Domestic Rabbit(100339094) mutL homolog 3 (E. coli)
- sheep(101109183) mutL homolog 3 (E. coli)
- dog(480389) mutL homolog 3 (E. coli)
- domestic guinea pig(100735009) mutL homolog 3 (E. coli)
- domestic cat(101096575) mutL homolog 3 (E. coli)
- Thale Cress(829704) DNA mismatch repair protein MLH3
- Zebrafish(568323) mutL homolog 3 (E. coli)
- Horse(100057292) mutL homolog 3 (E. coli)
- chicken(100859200) mutL homolog 3 (E. coli)
- naked mole-rat(101723287) mutL homolog 3 (E. coli)
- cow(786279) mutL homolog 3 (E. coli)
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Przeciwciało monoklonalne anty-Mlh3 wytwarzane u myszy, Prestige Antibodies® Powered by Atlas Antibodies, clone CL14084, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Przeciwciało monoklonalne anty-Mlh3 wytwarzane u myszy, Prestige Antibodies® Powered by Atlas Antibodies, clone CL14096, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-MLH3 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
western blot
Anti-MLH3 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Anti-MLH3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence