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Merck

MTRR

5-methyltetrahydrofolate-homocysteine methyltransferase reductase

Synonimy:
MSR, cblE
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(4552) Summary: Methionine is an essential amino acid required for protein synthesis and one-carbon metabolism. Its synthesis is catalyzed by the enzyme methionine synthase. Methionine synthase eventually becomes inactive due to the oxidation of its cob(I)alamin cofactor. The protein encoded by this gene regenerates a functional methionine synthase via reductive methylation. It is a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. Patients of the cbl-E complementation group of disorders of folate/cobalamin metabolism are defective in reductive activation of methionine synthase. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(210009) 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
  • Rat(290947) 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
  • domestic guinea pig(100732821) 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
  • Zebrafish(560667) 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
  • chicken(428502) 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
  • sheep(101123409) 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
  • Domestic Rabbit(100350605) 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
  • cow(507991) 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
  • domestic cat(101098359) 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
  • dog(478623) 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
  • naked mole-rat(101720530) 5-methyltetrahydrofolate-homocysteine methyltransferase reductase

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-MTRR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human MTRR,
Gatunek
human