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NDUFS2

NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)

Synonimy:
CI-49
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(4720) Summary: The protein encoded by this gene is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I). Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes. The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product. Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]
  • Mouse(226646) NADH dehydrogenase (ubiquinone) Fe-S protein 2
  • Rat(289218) NADH dehydrogenase (ubiquinone) Fe-S protein 2
  • Zebrafish(553672) NADH dehydrogenase (ubiquinone) Fe-S protein 2
  • chicken(100857596) NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
  • domestic guinea pig(100713270) NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
  • naked mole-rat(101701670) NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
  • dog(478981) NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
  • cow(327697) NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
  • sheep(101104108) NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
  • domestic cat(101088298) NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti NDUFS2 Antibody, clone 24GB495, Rabbit Monoclonal, clone 24GB495, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reaktywność gatunkowa
human, rat
Zastosowanie
immunofluorescence
western blot
Anti-NDUFS2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry

western blot
Anti-NDUFS2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
bovine, canine, human, mouse, rat
Zastosowanie
ELISA
western blot
Przeciwciało anty-NDUFS2produkowane u królików, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunofluorescence
immunohistochemistry

western blot
Anti-NDUFS2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
Metformina, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
Metformin hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Gatunek
human
Metformin hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Gatunek
human
Metformin hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
1,1-Dimethylbiguanide hydrochloride, 97%,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human NDUFS2,
Gatunek
human
MISSION® esiRNA, targeting mouse Ndufs2,
Gatunek
mouse