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Merck

NOD2

nucleotide-binding oligomerization domain containing 2

Synonimy:
ACUG, BLAU, CARD15, CD, CLR16.3, IBD1, NLRC2, NOD2B, PSORAS1
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(64127) Summary: This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. [provided by RefSeq, Jul 2008]
  • Mouse(257632) nucleotide-binding oligomerization domain containing 2
  • Rat(291912) nucleotide-binding oligomerization domain containing 2
  • Domestic Rabbit(100356594) nucleotide-binding oligomerization domain containing 2
  • sheep(780465) nucleotide-binding oligomerization domain containing 2
  • cow(444867) nucleotide-binding oligomerization domain containing 2
  • dog(487286) nucleotide-binding oligomerization domain containing 2
  • domestic cat(101096863) nucleotide-binding oligomerization domain containing 2
  • naked mole-rat(101709371) nucleotide-binding oligomerization domain containing 2
  • domestic guinea pig(100727812) nucleotide-binding oligomerization domain containing 2
  • Zebrafish(777696) nucleotide-binding oligomerization domain containing 2

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-NOD2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anti-NOD2 (ab2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunocytochemistry

immunofluorescence

western blot
Przeciwciało anty-NOD2, klon 2D9, clone 2D9, from mouse,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
immunoprecipitation (IP)

western blot

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse Nod2,
Gatunek
mouse
MISSION® esiRNA, targeting human NOD2,
Gatunek
human