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OTX2

orthodenticle homeobox 2

Synonimy:
CPHD6, MCOPS5
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(5015) Summary: This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine. [provided by RefSeq, Jul 2012]
  • Mouse(18424) orthodenticle homolog 2 (Drosophila)
  • Rat(305858) orthodenticle homeobox 2
  • domestic guinea pig(100729098) orthodenticle homeobox 2
  • domestic cat(101094107) orthodenticle homeobox 2
  • naked mole-rat(101696878) orthodenticle homeobox 2
  • sheep(101114527) orthodenticle homeobox 2
  • chicken(395191) orthodenticle homeobox 2
  • cow(538953) orthodenticle homeobox 2
  • Domestic Rabbit(100009374) orthodenticle homeobox 2
  • Zebrafish(30501) orthodenticle homolog 2
  • dog(490708) orthodenticle homeobox 2

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-OTX2 antibody produced in mouse, clone 1H12C4B5, ascites fluid,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
flow cytometry

immunofluorescence

immunohistochemistry

western blot
Anti-OTX2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
ChIP
immunohistochemistry
Anti-OTX2 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat, sheep
Zastosowanie
immunohistochemistry
western blot
Przeciwciało anty-OTX2, klon 6I3J0, królicze monoklonalne, ,
Reaktywność gatunkowa
human, rat
Zastosowanie
western blot
Anti-OTX2 Antibody, clone 1O4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
xenopus, bovine, horse, human, monkey, porcine, rat
Zastosowanie
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human OTX2,
Gatunek
human
MISSION® esiRNA, targeting mouse Otx2,
Gatunek
mouse