Przejdź do zawartości
Merck

PAK6

p21 protein (Cdc42/Rac)-activated kinase 6

Synonimy:
PAK5
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(56924) Summary: This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]
  • Mouse(214230) p21 protein (Cdc42/Rac)-activated kinase 6
  • Rat(296078) p21 protein (Cdc42/Rac)-activated kinase 6
  • domestic guinea pig(100713585) p21 protein (Cdc42/Rac)-activated kinase 6
  • naked mole-rat(101706200) p21 protein (Cdc42/Rac)-activated kinase 6
  • chicken(428837) p21 protein (Cdc42/Rac)-activated kinase 6
  • Domestic Rabbit(100348921) p21 protein (Cdc42/Rac)-activated kinase 6
  • dog(487490) p21 protein (Cdc42/Rac)-activated kinase 6
  • domestic cat(101091201) p21 protein (Cdc42/Rac)-activated kinase 6
  • Horse(100071463) p21 protein (Cdc42/Rac)-activated kinase 6
  • cow(539224) p21 protein (Cdc42/Rac)-activated kinase 6
  • Goat(100860973) p21 protein (Cdc42/Rac)-activated kinase 6
  • sheep(101112573) p21 protein (Cdc42/Rac)-activated kinase 6

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-PAK6 (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, canine, goat, guinea pig, horse, human, mouse, rabbit
Zastosowanie
western blot
Anti-phospho-PAK4 /PAK5 /PAK6 (Ser474 /Ser560/ Ser602) Antibody, clone 24GB445, Rabbit Monoclonal, clone 24GB445, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reaktywność gatunkowa
human, rat
Zastosowanie
flow cytometry
immunofluorescence

western blot
Anti-phospho-PAK5/6 (pSer602/560) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
western blot
Anti-Phospho-PAK4/PAK5/PAK6-S474/S560/S602, ,
Reaktywność gatunkowa
human, mouse
Zastosowanie
western blot

Proteins

Numer produktu
Opis
Gatunek
PAK6, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human PAK6, BUB1B-PAK6,
Gatunek
human