Przejdź do zawartości
Merck

PARN

poly(A)-specific ribonuclease

Synonimy:
DAN
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(5073) Summary: The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
  • Mouse(74108) poly(A)-specific ribonuclease (deadenylation nuclease)
  • Rat(360464) poly(A)-specific ribonuclease
  • domestic guinea pig(100732149) poly(A)-specific ribonuclease
  • naked mole-rat(101715275) poly(A)-specific ribonuclease
  • cow(524155) poly(A)-specific ribonuclease
  • Zebrafish(791461) poly(A)-specific ribonuclease (deadenylation nuclease)
  • Domestic Rabbit(100351489) poly(A)-specific ribonuclease
  • domestic cat(101100021) poly(A)-specific ribonuclease
  • dog(479839) poly(A)-specific ribonuclease
  • chicken(416423) poly(A)-specific ribonuclease
  • sheep(101112185) poly(A)-specific ribonuclease

Custom & Knockdown Gene Products

ELISA

Numer produktu
Opis
Gatunek
Mouse Parn / Poly(A)-specific Ribonuclease PARN ELISA Kit, for serum, plasma and cell culture supernatants,
Gatunek
mouse

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-PARN antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
Anti-PARN antibody produced in rabbit, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse Parn,
Gatunek
mouse
MISSION® esiRNA, targeting human PARN,
Gatunek
human