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Merck

PARP2

poly (ADP-ribose) polymerase 2

Synonimy:
ADPRT2, ADPRTL2, ADPRTL3, ARTD2, PARP-2, pADPRT-2
Gatunek:
Human PARP2 (10038), Mouse Parp2 (11546), Rat Parp2 (290027), Zebrafish parp2 (100007906), sheep PARP2 (101118027), dog PARP2 (475392), domestic cat PARP2 (101090944), Horse PARP2 (100072572), domestic guinea pig Parp2 (100720452), cow PARP2 (505828)
Identyfikator UniProtKB:
Q9UGN5, Q8TEU4, Q9NUV2, Q9UMR4, Q9Y6C8
Identyfikator genu:
  • Human(10038) Summary: This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jul 2008]
  • Mouse(11546) poly (ADP-ribose) polymerase family, member 2
  • Rat(290027) poly (ADP-ribose) polymerase 2
  • Zebrafish(100007906) poly (ADP-ribose) polymerase family, member 2
  • sheep(101118027) poly (ADP-ribose) polymerase 2
  • dog(475392) poly (ADP-ribose) polymerase 2
  • domestic cat(101090944) poly (ADP-ribose) polymerase 2
  • Horse(100072572) poly (ADP-ribose) polymerase 2
  • domestic guinea pig(100720452) poly (ADP-ribose) polymerase 2
  • cow(505828) poly (ADP-ribose) polymerase 2

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
HPA052003
Anti-PARP2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry
western blot
SAB5702581
Przeciwciało anty-PARP2, klon 6G5U7, królicze monoklonalne, ,
Reaktywność gatunkowa
human, rat
Zastosowanie
western blot
SAB1304746
ANTI-PARP2 (N-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Reaktywność gatunkowa
mouse
Zastosowanie
western blot
SAB2108489
Anti-PARP2, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
western blot
P248
Monoclonal Anti-PARP antibody produced in mouse, clone C-2-10, ascites fluid,
Reaktywność gatunkowa
hamster, mouse, primate, rat
Zastosowanie
ELISA
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot

Cell Lines

Numer produktu
Opis
Gatunek
CLLS1066
MCF10A CELLS PARP2 (-/-), ,
Gatunek
human

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
N7287
NU-1025, ≥97% (HPLC), solid,
Gatunek
mouse
H57807
4-Hydroxyquinazoline, 98%,
Gatunek
mouse

Proteins

Numer produktu
Opis
Gatunek
SRP0193
PARP2 Active human, recombinant, expressed in baculovirus infected insect cells, ≥60% (SDS-PAGE),
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
EHU025371
MISSION® esiRNA, targeting human PARP2,
Gatunek
human
EMU020061
MISSION® esiRNA, targeting mouse Parp2,
Gatunek
mouse