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Merck

PDE4C

phosphodiesterase 4C, cAMP-specific

Synonimy:
DPDE1
Gatunek:
Human PDE4C (5143), Mouse Pde4c (110385), Rat Pde4c (290646), dog PDE4C (609938), cow PDE4C (524624), domestic cat PDE4C (101086123), naked mole-rat Pde4c (101703048), sheep PDE4C (101111282)
Identyfikator UniProtKB:
Q08493, B3KTC4, Q9UN44, Q9UN45, Q9UN46, Q9UPJ6
Identyfikator genu:
  • Human(5143) Summary: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
  • Mouse(110385) phosphodiesterase 4C, cAMP specific
  • Rat(290646) phosphodiesterase 4C, cAMP-specific
  • dog(609938) phosphodiesterase 4C, cAMP-specific
  • cow(524624) phosphodiesterase 4C, cAMP-specific
  • domestic cat(101086123) phosphodiesterase 4C, cAMP-specific
  • naked mole-rat(101703048) phosphodiesterase 4C, cAMP-specific
  • sheep(101111282) phosphodiesterase 4C, cAMP-specific

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Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
PHR1023
Theophylline, Pharmaceutical Secondary Standard; Certified Reference Material,
Gatunek
human
PHL82668
Theophylline, phyproof® Reference Substance,
Gatunek
human
1653117
Wzorzec temperatury topnienia teofiliny, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
BP327
Theophylline, British Pharmacopoeia (BP) Reference Standard,
Gatunek
human
T0800000
Theophylline, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
SAB1400197
Monoclonal Anti-PDE4C antibody produced in mouse, clone 6A10, ascites fluid,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
HPA054218
Anty-PDE4C, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
SAB1404183
Monoclonal Anti-PDE4C, (N-terminal) antibody produced in mouse, clone 4E5, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunofluorescence
western blot
HPA048975
Anti-PDE4C antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
I0157
Ibudilast, ≥99% (HPLC), solid,
Gatunek
human
SML1099
Roflumilast, ≥98% (HPLC),
Gatunek
human
SML0517
Amlexanox, ≥98% (HPLC),
Gatunek
human
D0633
7-(2,3-Dihydroxypropyl)theophylline, ,
Gatunek
human
1231502
Dyfilina, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human

Proteins

Numer produktu
Opis
Gatunek
SRP0266
PDE4C1 Active human, recombinant, expressed in baculovirus infected insect cells, ≥80% (SDS-PAGE),
Gatunek
human
SRP0265
PDE4C Active from mouse, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),
Gatunek
mouse

esiRNA

Numer produktu
Opis
Gatunek
EMU043571
MISSION® esiRNA, targeting mouse Pde4c,
Gatunek
mouse
EHU060201
MISSION® esiRNA, targeting human PDE4C,
Gatunek
human