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Merck

PEG3

paternally expressed 3

Synonimy:
PW1, ZKSCAN22, ZNF904, ZSCAN24
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(5178) Summary: In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5' exons and a common promoter and both genes are paternally expressed (PMID:15203203). Alternative splicing events connect their shared 5' exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons. Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis. PEG3 has also shown tumor suppressor activity and tumorigenesis in glioma and ovarian cells. Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2009]
  • Mouse(18616) paternally expressed 3
  • Rat(246361) paternally expressed 3
  • dog(476371) paternally expressed 3
  • sheep(100505405) paternally expressed 3
  • domestic cat(100510800) paternally expressed 3
  • cow(444864) paternally expressed 3
  • naked mole-rat(101714488) paternally expressed 3
  • sheep(101112254) paternally expressed 3

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-PEG3 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, dog, horse, human, pig, rabbit
Zastosowanie
western blot

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human PEG3,
Gatunek
human