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Merck

PILRA

paired immunoglobin-like type 2 receptor alpha

Synonimy:
FDF03
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(29992) Summary: Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This particular gene encodes the ITIM-bearing member of the receptor pair, which functions in the inhibitory role. Alternative splicing has been observed at this locus and three variants, each encoding a distinct isoform, are described. [provided by RefSeq, Jul 2008]
  • Mouse(231805) paired immunoglobin-like type 2 receptor alpha
  • Rat(288568) paired immunoglobin-like type 2 receptor alpha
  • dog(489841) paired immunoglobin-like type 2 receptor alpha
  • domestic guinea pig(100715696) paired immunoglobin-like type 2 receptor alpha
  • sheep(101122158) paired immunoglobin-like type 2 receptor alpha
  • naked mole-rat(101721193) paired immunoglobin-like type 2 receptor alpha
  • cow(100137734) paired immunoglobin-like type 2 receptor alpha

Custom & Knockdown Gene Products

ELISA

Numer produktu
Opis
Gatunek
Human PILR-alpha ELISA, for serum, plasma and cell culture supernatants,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-PILRA antibody produced in mouse, clone 3C2, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
Anty-PILRA, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anti-PILRα Antibody, clone 5F10, ,
Reaktywność gatunkowa
mouse
Zastosowanie
ELISA
flow cytometry

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human PILRA,
Gatunek
human
MISSION® esiRNA, targeting mouse Pilra,
Gatunek
mouse