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PIN1

peptidylprolyl cis/trans isomerase, NIMA-interacting 1

Synonimy:
DOD, UBL5
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(5300) Summary: Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. This gene encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival. This enzyme also plays a key role in the pathogenesis of Alzheimer's disease and many cancers. Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jun 2011]
  • Mouse(23988) protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1
  • Rat(298696) peptidylprolyl cis/trans isomerase, NIMA-interacting 1
  • Thale Cress(843693) auxin efflux carrier component 1
  • Zebrafish(393721) protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1
  • chicken(100859153) peptidylprolyl cis/trans isomerase, NIMA-interacting 1
  • dog(484963) peptidylprolyl cis/trans isomerase, NIMA-interacting 1
  • domestic cat(101087904) peptidylprolyl cis/trans isomerase, NIMA-interacting 1
  • cow(535470) peptidylprolyl cis/trans isomerase, NIMA-interacting 1
  • sheep(101110756) peptidylprolyl cis/trans isomerase, NIMA-interacting 1
  • domestic guinea pig(100726337) peptidylprolyl cis/trans isomerase, NIMA-interacting 1
  • naked mole-rat(101708402) peptidylprolyl cis/trans isomerase, NIMA-interacting 1

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-PIN1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
western blot
Przeciwciało anty-Pin1, klon 5B4.1, clone 5B4.1, from mouse,
Reaktywność gatunkowa
human, rat
Zastosowanie
immunohistochemistry
western blot
Anty-PIN1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
Anti-PIN1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
canine, human, mouse, rat
Zastosowanie
ELISA
western blot
Anty-fosfo-Pin1(pSer16), affinity isolated antibody,
Reaktywność gatunkowa
human, mouse
Zastosowanie
western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
Cycloheximide, Biotechnology Performance Certified,
Gatunek
human
Cycloheximide, ≥95% (HPLC),
Gatunek
human
Cycloheximide, from microbial, ≥94% (TLC),
Gatunek
human
Cycloheximide solution, Ready-Made Solution, microbial, 100 mg/mL in DMSO, Suitable for cell culture,
Gatunek
human
Cycloheximide solution, 0.1%, suitable for microbiology,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse Pin1,
Gatunek
mouse
MISSION® esiRNA, targeting human PIN1,
Gatunek
human