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PLAUR

plasminogen activator, urokinase receptor

Synonimy:
CD87, U-PAR, UPAR, URKR
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(5329) Summary: This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. [provided by RefSeq, Jul 2008]
  • Mouse(18793) plasminogen activator, urokinase receptor
  • Rat(50692) plasminogen activator, urokinase receptor
  • dog(476446) plasminogen activator, urokinase receptor
  • Horse(100033904) plasminogen activator, urokinase receptor
  • domestic cat(101091240) plasminogen activator, urokinase receptor
  • sheep(100302564) plasminogen activator, urokinase receptor
  • cow(281983) plasminogen activator, urokinase receptor
  • domestic guinea pig(100715207) plasminogen activator, urokinase receptor
  • naked mole-rat(101705929) plasminogen activator, urokinase receptor

Custom & Knockdown Gene Products

ELISA

Numer produktu
Opis
Gatunek
Human PLAUR / Urokinase Plasminogen Activator Surface Receptor ELISA Kit, ,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-PLAUR/uPAR antibody, Mouse monoclonal, clone PL231, purified from hybridoma cell culture,
Reaktywność gatunkowa
canine, human, monkey, mouse, rat
Zastosowanie
immunofluorescence
western blot
Anti-PLAUR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anti-PLAUR antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry

western blot
Anti-uPAR Antibody, clone 2G10 , ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
human
Zastosowanie
flow cytometry
immunocytochemistry

immunohistochemistry

inhibition assay

western blot
Przeciwciało anty-uPAR (CD87), klon 5D6, clone 5D6, from mouse,
Reaktywność gatunkowa
hamster
Zastosowanie
flow cytometry
immunocytochemistry

western blot

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse Plaur,
Gatunek
mouse
MISSION® esiRNA, targeting human PLAUR,
Gatunek
human