PNP
purine nucleoside phosphorylase
Synonimy:
NP, PRO1837, PUNP
Gatunek:
Human PNP (4860), Mouse Pnp (18950), Rat Pnp (290029), chicken PNP (769958), domestic cat PNP (101081226), dog PNP (475393), cow PNP (493724), naked mole-rat Pnp (101708512), domestic guinea pig Pnp (100718329)
Identyfikator UniProtKB:
Identyfikator genu:
- Human(4860) Summary: This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2. [provided by RefSeq, Jul 2008]
- Mouse(18950) purine-nucleoside phosphorylase
- Rat(290029) purine nucleoside phosphorylase
- chicken(769958) purine nucleoside phosphorylase
- domestic cat(101081226) purine nucleoside phosphorylase
- dog(475393) purine nucleoside phosphorylase
- cow(493724) purine nucleoside phosphorylase
- naked mole-rat(101708512) purine nucleoside phosphorylase
- domestic guinea pig(100718329) purine nucleoside phosphorylase
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Numer produktu
Opis
Gatunek
esiRNA
Numer produktu
Opis
Gatunek