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POLR2A

polymerase (RNA) II (DNA directed) polypeptide A, 220kDa

Synonimy:
POLR2, POLRA, RPB1, RPBh1, RPO2, RPOL2, RpIILS, hRPB220, hsRPB1
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(5430) Summary: This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq, Jul 2008]
  • Mouse(20020) polymerase (RNA) II (DNA directed) polypeptide A
  • Rat(363633) polymerase (RNA) II (DNA directed) polypeptide A
  • cow(282312) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
  • naked mole-rat(101725588) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
  • dog(479483) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
  • Zebrafish(553347) polymerase (RNA) II (DNA directed) polypeptide A
  • sheep(100144762) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
  • domestic cat(101098500) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
  • domestic guinea pig(100734232) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-phospho RNA Pol II (Ser2), clone 3E7C7 Antibody, clone 3E7C7, from rat,
Reaktywność gatunkowa
canine, human, monkey, mouse, rat
Zastosowanie
ChIP
ELISA

immunocytochemistry

western blot
Anti-phospho RNA Pol II (Ser5), clone 1H4B6 Antibody, clone 1H4B6, from rat,
Reaktywność gatunkowa
canine, human, monkey, mouse, rat
Zastosowanie
ChIP
ELISA

immunocytochemistry

western blot
Przeciwciało przeciwko polimerazie II RNA, przeciwciało CTD, klon 8WG16, clone 8WG16, from mouse,
Reaktywność gatunkowa
human, yeast
Zastosowanie
dot blot
immunoprecipitation (IP)

inhibition assay

western blot
Anti-POLR2A Antibody, clone 3G21 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunocytochemistry
immunohistochemistry

western blot
Anti-POLR2A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry

Proteins

Numer produktu
Opis
Gatunek
RNA Polymerase II, C-terminal human, recombinant, expressed in E. coli, ≥85% (SDS-PAGE),
Gatunek
human
RNA Polymerase II, C-terminal domain, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human POLR2A,
Gatunek
human
MISSION® esiRNA, targeting mouse Polr2a,
Gatunek
mouse