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Merck

POT1

protection of telomeres 1

Synonimy:
HPOT1
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(25913) Summary: This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]
  • Rat(500054) protection of telomeres 1
  • chicken(404538) protection of telomeres 1 homolog (S. pombe)
  • Zebrafish(566847) protection of telomeres 1 homolog
  • domestic guinea pig(100725051) protection of telomeres 1
  • naked mole-rat(101698900) protection of telomeres 1
  • sheep(101107695) protection of telomeres 1 homolog (S. pombe)
  • cow(511292) protection of telomeres 1
  • Horse(100071610) protection of telomeres 1 homolog (S. pombe)
  • domestic cat(101097225) protection of telomeres 1 homolog (S. pombe)
  • dog(609119) protection of telomeres 1 homolog (S. pombe)

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anty-POT1, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anty-POT1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human POT1,
Gatunek
human