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PRCP

prolylcarboxypeptidase (angiotensinase C)

Synonimy:
HUMPCP, PCP
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(5547) Summary: The protein encoded by this gene is a lysosomal prolylcarboxypeptidase, which cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH, but the enzyme activity is retained with some substrates at neutral pH. This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
  • Mouse(72461) prolylcarboxypeptidase (angiotensinase C)
  • Rat(293118) prolylcarboxypeptidase (angiotensinase C)
  • sheep(101107644) prolylcarboxypeptidase (angiotensinase C)
  • Horse(100061830) prolylcarboxypeptidase (angiotensinase C)
  • domestic cat(101100665) prolylcarboxypeptidase (angiotensinase C)
  • cow(534927) prolylcarboxypeptidase (angiotensinase C)
  • naked mole-rat(101719590) prolylcarboxypeptidase (angiotensinase C)
  • chicken(428096) prolylcarboxypeptidase (angiotensinase C)
  • dog(476788) prolylcarboxypeptidase (angiotensinase C)
  • Zebrafish(436967) prolylcarboxypeptidase (angiotensinase C)
  • domestic guinea pig(100734342) prolylcarboxypeptidase (angiotensinase C)

Custom & Knockdown Gene Products

ELISA

Numer produktu
Opis
Gatunek
Human PRCP ELISA, for serum, plasma and cell culture supernatants,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-PRCP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot
Anty-PRCP, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
western blot

Proteins

Numer produktu
Opis
Gatunek
PrCP active human, recombinant, expressed in FreeStyle 293-F cells, ≥15% (SDS-PAGE),
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human PRCP,
Gatunek
human
MISSION® esiRNA, targeting mouse Prcp,
Gatunek
mouse