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PRMT6

protein arginine methyltransferase 6

Synonimy:
HRMT1L6
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(55170) Summary: The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity. [provided by RefSeq, Sep 2011]
  • Mouse(99890) protein arginine N-methyltransferase 6
  • Rat(295384) protein arginine methyltransferase 6
  • domestic cat(101093626) protein arginine methyltransferase 6
  • domestic guinea pig(100725259) protein arginine methyltransferase 6
  • cow(540228) protein arginine methyltransferase 6
  • Thale Cress(821541) protein arginine N-methyltransferase 6
  • naked mole-rat(101715374) protein arginine methyltransferase 6
  • sheep(101119859) protein arginine methyltransferase 6
  • Zebrafish(448867) protein arginine methyltransferase 6
  • dog(490133) protein arginine methyltransferase 6

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Przeciwciało anty-PRMT6, klon 1Z10L6, królicze monoklonalne, ,
Reaktywność gatunkowa
human, rat
Zastosowanie
western blot
Anti-PRMT6 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse, pig, rat
Zastosowanie
ELISA
western blot
Anti-PRMT6 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, rat
Zastosowanie
ChIP
western blot
Anty-PRMT6, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
Anti-PRMT6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry

Proteins

Numer produktu
Opis
Gatunek
PRMT6 active human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
Gatunek
human
PRMT6 human, recombinant, expressed in FreeStyle 293-F cells, ≥70% (SDS-PAGE),
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human PRMT6,
Gatunek
human
MISSION® esiRNA, targeting mouse Prmt6,
Gatunek
mouse