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Merck

PTPRA

protein tyrosine phosphatase, receptor type, A

Synonimy:
HEPTP, HLPR, HPTPA, HPTPalpha, LRP, PTPA, PTPRL2, R-PTP-alpha, RPTPA
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(5786) Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(19262) protein tyrosine phosphatase, receptor type, A
  • Rat(25167) protein tyrosine phosphatase, receptor type, A
  • Zebrafish(140818) protein tyrosine phosphatase, receptor type, A
  • chicken(396060) protein tyrosine phosphatase, receptor type, A
  • domestic cat(101096558) protein tyrosine phosphatase, receptor type, A
  • Horse(100066880) protein tyrosine phosphatase, receptor type, A
  • dog(477176) protein tyrosine phosphatase, receptor type, A
  • sheep(101101909) protein tyrosine phosphatase, receptor type, A
  • cow(100138017) protein tyrosine phosphatase, receptor type, A
  • Domestic Rabbit(100342875) protein tyrosine phosphatase, receptor type, A
  • naked mole-rat(101716097) protein tyrosine phosphatase, receptor type, A
  • domestic guinea pig(100720460) protein tyrosine phosphatase, receptor type, A

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-PTPRA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot
Anty-PTPRA, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
Przeciwciało anty-fosfo-PTPRA-Y789wytwarzane u królika, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
Milrinone, ≥97% (TLC), powder,
Gatunek
rat, human

Proteins

Numer produktu
Opis
Gatunek
PTPRA (174-802), active, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human PTPRA, VPS16,
Gatunek
human
MISSION® esiRNA, targeting mouse Ptpra,
Gatunek
mouse