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Merck

PTPRN

protein tyrosine phosphatase, receptor type, N

Synonimy:
IA-2, IA-2/PTP, IA2, ICA512, R-PTP-N
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(5798) Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010]
  • Mouse(19275) protein tyrosine phosphatase, receptor type, N
  • Rat(116660) protein tyrosine phosphatase, receptor type, N
  • Domestic Rabbit(100355368) protein tyrosine phosphatase, receptor type, N
  • domestic cat(101100657) protein tyrosine phosphatase, receptor type, N
  • dog(478921) protein tyrosine phosphatase, receptor type, N
  • cow(286810) protein tyrosine phosphatase, receptor type, N
  • sheep(101113312) protein tyrosine phosphatase, receptor type, N
  • domestic guinea pig(100733759) protein tyrosine phosphatase, receptor type, N
  • naked mole-rat(101718650) protein tyrosine phosphatase, receptor type, N

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-PTPRN antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Monoclonal Anti-PTPRN antibody produced in mouse, clone 8E3, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
Anti-ICA 512/RESP18 Antibody, clone 1348-D29-1, ,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
western blot
Anti-PTPRN antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
Anti-IA2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
western blot

Proteins

Numer produktu
Opis
Gatunek
PTPIA2 Active human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human PTPRN,
Gatunek
human
MISSION® esiRNA, targeting mouse Ptprn,
Gatunek
mouse