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Merck

RAD51

RAD51 recombinase

Synonimy:
BRCC5, HRAD51, HsRad51, HsT16930, MRMV2, RAD51A, RECA
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(5888) Summary: The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]
  • Mouse(19361) RAD51 homolog
  • Rat(499870) RAD51 recombinase
  • domestic cat(101089015) RAD51 homolog (S. cerevisiae)
  • domestic guinea pig(100716391) RAD51 homolog (S. cerevisiae)
  • Domestic Rabbit(100008661) RAD51 homolog (S. cerevisiae)
  • naked mole-rat(101715048) RAD51 homolog (S. cerevisiae)
  • chicken(396086) RAD51 homolog (S. cerevisiae)
  • Zebrafish(406487) RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)
  • Thale Cress(832208) DNA repair protein RAD51-like 1
  • dog(403568) RAD51 homolog (S. cerevisiae)
  • sheep(101109275) RAD51 homolog (S. cerevisiae)
  • cow(514749) RAD51 homolog (S. cerevisiae)

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-Rad51 (Ab-1) Rabbit pAb, liquid, Calbiochem®,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
Anti-RAD51 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, guinea pig, horse, human, mouse, rabbit, rat
Zastosowanie
immunohistochemistry
western blot
Anti-RAD51 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
Anti-phospho-RAD51 (pTyr315) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
western blot
Przeciwciało anty-Rad51, klon 5S9B0, królicze monoklonalne, ,
Reaktywność gatunkowa
human, rat
Zastosowanie
ChIP
western blot

Proteins

Numer produktu
Opis
Gatunek
RAD51 human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human RAD51,
Gatunek
human