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RNF20

ring finger protein 20, E3 ubiquitin protein ligase

Synonimy:
BRE1, BRE1A, hBRE1
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(56254) Summary: The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor. This gene selectively suppresses the expression of some genes by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS). [provided by RefSeq, Feb 2012]
  • Mouse(109331) ring finger protein 20
  • Rat(313216) ring finger protein 20, E3 ubiquitin protein ligase
  • Zebrafish(402838) ring finger protein 20, E3 ubiquitin protein ligase
  • domestic cat(101097522) ring finger protein 20, E3 ubiquitin protein ligase
  • cow(513326) ring finger protein 20
  • dog(474788) ring finger protein 20, E3 ubiquitin protein ligase
  • chicken(427310) ring finger protein 20, E3 ubiquitin protein ligase
  • naked mole-rat(101711656) ring finger protein 20, E3 ubiquitin protein ligase
  • domestic guinea pig(100717191) ring finger protein 20, E3 ubiquitin protein ligase
  • Domestic Rabbit(100340973) ring finger protein 20, E3 ubiquitin protein ligase
  • Horse(100054384) ring finger protein 20, E3 ubiquitin protein ligase
  • sheep(101121065) ring finger protein 20, E3 ubiquitin protein ligase

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-RNF20 antibody produced in mouse, clone 1C6, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
Przeciwciało anty-RNF20, klon 8N4O8, królicze monoklonalne, ,
Reaktywność gatunkowa
mouse
Zastosowanie
western blot
Przeciwciało anty-Rnf20 wytwarzane u królików, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
Anty-RNF20, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
Przeciwciało anty-HRNF20, from rabbit, purified by affinity chromatography,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
western blot

Proteins

Numer produktu
Opis
Gatunek
RNF20 active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥50% (SDS-PAGE),
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human RNF20,
Gatunek
human