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SAV1

salvador homolog 1 (Drosophila)

Synonimy:
SAV, WW45, WWP4
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(60485) Summary: WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor. [provided by RefSeq, Aug 2012]
  • Mouse(64010) salvador homolog 1 (Drosophila)
  • Rat(299116) salvador homolog 1 (Drosophila)
  • chicken(423578) salvador homolog 1 (Drosophila)
  • dog(480319) salvador homolog 1 (Drosophila)
  • domestic cat(101096154) salvador homolog 1 (Drosophila)
  • naked mole-rat(101726669) salvador homolog 1 (Drosophila)
  • Horse(100066557) salvador homolog 1 (Drosophila)
  • sheep(101104666) salvador homolog 1 (Drosophila)
  • Domestic Rabbit(100350937) salvador homolog 1 (Drosophila)
  • domestic guinea pig(100728249) salvador homolog 1 (Drosophila)
  • Zebrafish(447821) salvador homolog 1 (Drosophila)
  • cow(516557) salvador homolog 1 (Drosophila)

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-SAV1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry

western blot
Anty-SAV1, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
Przeciwciało anty-SAV1, klon 3A1.1, clone 3A1.1, from mouse,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot
Anti-Sav1 (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, canine, horse, human, mouse, pig, rabbit, rat
Zastosowanie
western blot

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human SAV1,
Gatunek
human
MISSION® esiRNA, targeting mouse Sav1,
Gatunek
mouse