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Merck

SCN7A

sodium channel, voltage-gated, type VII, alpha subunit

Synonimy:
NaG, Nav2.1, Nav2.2, SCN6A
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(6332) Summary: This gene encodes one of the many voltage-gated sodium channel proteins. For proper functioning of neurons and muscles during action potentials, voltage-gated sodium channels direct sodium ion diffusion for membrane depolarization. This sodium channel protein has some atypical characteristics; the similarity between the human and mouse proteins is lower compared to other orthologous sodium channel pairs. Also, the S4 segments, which sense voltage changes, have fewer positive charged residues that in other sodium channels; domain 4 has fewer arginine and lysine residues compared to other sodium channel proteins. Several alternatively spliced transcript variants exist, but the full-length natures of all of them remain unknown. [provided by RefSeq, Dec 2011]
  • Mouse(20272) sodium channel, voltage-gated, type VII, alpha
  • Rat(64155) sodium channel, voltage-gated, type VII, alpha
  • naked mole-rat(101711842) sodium channel, voltage-gated, type VII, alpha subunit
  • domestic guinea pig(100715553) sodium channel, voltage-gated, type VII, alpha subunit
  • dog(488382) sodium channel, voltage-gated, type VII, alpha subunit
  • Horse(100062186) sodium channel, voltage-gated, type VII, alpha subunit
  • cow(507516) sodium channel, voltage-gated, type VII, alpha subunit
  • sheep(101109522) sodium channel, voltage-gated, type VII, alpha subunit
  • domestic cat(101082080) sodium channel, voltage-gated, type VII, alpha subunit

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-SCN7A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anty-SCN7A, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry

Small Molecule - Blocker

Numer produktu
Opis
Gatunek
Phenazopyridine hydrochloride, VETRANAL®, analytical standard,
Gatunek
human
Rufinamide, ≥98% (HPLC), powder,
Gatunek
human
Procaine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Tetracaine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Zonisamide solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse Scn7a,
Gatunek
mouse