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Merck

SCN8A

sodium channel, voltage gated, type VIII, alpha subunit

Synonimy:
CERIII, CIAT, EIEE13, MED, NaCh6, Nav1.6, PN4
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(6334) Summary: This gene encodes a member of the sodium channel alpha subunit gene family. The encoded protein forms the ion pore region of the voltage-gated sodium channel. This protein is essential for the rapid membrane depolarization that occurs during the formation of the action potential in excitable neurons. Mutations in this gene are associated with mental retardation, pancerebellar atrophy and ataxia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
  • Mouse(20273) sodium channel, voltage-gated, type VIII, alpha
  • Rat(29710) sodium channel, voltage gated, type VIII, alpha subunit
  • chicken(100857835) sodium channel, voltage gated, type VIII, alpha subunit
  • dog(477604) sodium channel, voltage gated, type VIII, alpha subunit
  • Horse(100052777) sodium channel, voltage gated, type VIII, alpha subunit
  • cow(537277) sodium channel, voltage gated, type VIII, alpha subunit
  • naked mole-rat(101711868) sodium channel, voltage gated, type VIII, alpha subunit
  • domestic guinea pig(100734003) sodium channel, voltage gated, type VIII, alpha subunit
  • sheep(101113744) sodium channel, voltage gated, type VIII, alpha subunit
  • domestic cat(101096578) sodium channel, voltage gated, type VIII, alpha subunit
  • chicken(426869) sodium channel, voltage gated, type VIII, alpha subunit

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-SCN8A, affinity isolated antibody,
Reaktywność gatunkowa
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Zastosowanie
western blot
Monoclonal Anti-SCN8A antibody produced in mouse, clone 4G7, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunofluorescence

western blot
Anty-SCN8A, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
Anti-SCN8A Sodium Channel Antibody, Chemicon®, from rabbit,
Reaktywność gatunkowa
mouse, rat
Zastosowanie
immunocytochemistry
immunohistochemistry

western blot
Anty-SCN8A, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence

Small Molecule - Blocker

Numer produktu
Opis
Gatunek
Lidocaine, Pharmaceutical Secondary Standard; Certified Reference Material,
Gatunek
human
Rufinamide, ≥98% (HPLC), powder,
Gatunek
human
Tetracaine hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Gatunek
human
Procaine hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Gatunek
human
Tetracaine hydrochloride, ≥99%,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse Scn8a,
Gatunek
mouse