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SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

Synonimy:
PAI, PAI-1, PAI1, PLANH1
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(5054) Summary: This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
  • Mouse(18787) serine (or cysteine) peptidase inhibitor, clade E, member 1
  • Rat(24617) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • cow(281375) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • Zebrafish(100136840) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • domestic guinea pig(100725387) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • naked mole-rat(101703903) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • Domestic Rabbit(100009588) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • dog(403476) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • domestic cat(100127105) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

Custom & Knockdown Gene Products

ELISA

Numer produktu
Opis
Gatunek
Human PAI-1 ELISA Kit, for serum, plasma, cell culture supernatant.,
Gatunek
human
Rhesus Macaque PAI-1 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Gatunek

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-SerPINE1 (AB2) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, dog, horse, human, pig, rabbit, rat, sheep
Zastosowanie
western blot
Anti-SerPINE1 (AB1) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, human, mouse, pig, rabbit, rat, sheep
Zastosowanie
immunohistochemistry
western blot
Anti-SERPINE1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry
Przeciwciało anty-PAI-1/Serpin E1, klon 6L6Y7, królicze monoklonalne, ,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Przeciwciało anty-SERPINE1produkowane u królików, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunofluorescence
western blot

Proteins

Numer produktu
Opis
Gatunek
Plasminogen activator inhibitor 1 (PAI-1) human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human SERPINE1,
Gatunek
human
MISSION® esiRNA, targeting mouse Serpine1,
Gatunek
mouse