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SPHK1

sphingosine kinase 1

Synonimy:
SPHK
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(8877) Summary: The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
  • Mouse(20698) sphingosine kinase 1
  • Rat(170897) sphingosine kinase 1
  • Thale Cress(828239) sphingosine kinase 1
  • Horse(100058875) sphingosine kinase 1
  • domestic cat(101084918) sphingosine kinase 1
  • dog(483329) sphingosine kinase 1
  • domestic guinea pig(100727266) sphingosine kinase 1
  • naked mole-rat(101711606) sphingosine kinase 1
  • chicken(427803) sphingosine kinase 1
  • cow(618605) sphingosine kinase 1
  • sheep(101105263) sphingosine kinase 1

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-SPHK1 antibody produced in mouse, clone 1D6, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
Anti-SPHK1 Antibody, clone 2H5 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
human
Zastosowanie
affinity binding assay
immunoprecipitation (IP)

western blot
Anti-SPHK1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
bovine, canine, human, mouse, rat
Zastosowanie
ELISA
western blot

Proteins

Numer produktu
Opis
Gatunek
Sphingosine Kinase 1 human, aqueous glycerol solution,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human SPHK1,
Gatunek
human
MISSION® esiRNA, targeting mouse Sphk1,
Gatunek
mouse