STAT5A
signal transducer and activator of transcription 5A
Synonimy:
MGF, STAT5
Gatunek:
Human STAT5A (6776), Mouse Stat5a (20850), Rat Stat5a (24918), dog STAT5A (490968), naked mole-rat Stat5a (101723770), domestic cat STAT5A (101090913), domestic guinea pig Stat5a (100716811), cow STAT5A (282375), Horse STAT5A (100052904), sheep STAT5A (443419)
Identyfikator UniProtKB:
Identyfikator genu:
- Human(6776) Summary: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. [provided by RefSeq, Jul 2008]
- Mouse(20850) signal transducer and activator of transcription 5A
- Rat(24918) signal transducer and activator of transcription 5A
- dog(490968) signal transducer and activator of transcription 5A
- naked mole-rat(101723770) signal transducer and activator of transcription 5A
- domestic cat(101090913) signal transducer and activator of transcription 5A
- domestic guinea pig(100716811) signal transducer and activator of transcription 5A
- cow(282375) signal transducer and activator of transcription 5A
- Horse(100052904) signal transducer and activator of transcription 5A
- sheep(443419) signal transducer and activator of transcription 5A
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ELISA
Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
KD-Validated Anti STAT5A Antibody, clone 24GB1920, Rabbit Monoclonal, clone 24GB1920, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reaktywność gatunkowa
human
Zastosowanie
flow cytometry
western blot
western blot
Anti-phospho-STAT5A (pTyr694) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
western blot
Anti-STAT5A antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunofluorescence
western blot
western blot
Anti-Phospho-STAT5A-Y694, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
western blot
Anti-Phospho-STAT5A-Y694, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
western blot
Proteins
Numer produktu
Opis
Gatunek
STAT5, His tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Gatunek
human