STIM1
stromal interaction molecule 1
Synonimy:
D11S4896E, GOK, TAM
Gatunek:
Human STIM1 (6786), Mouse Stim1 (20866), Rat Stim1 (361618), dog STIM1 (608643), naked mole-rat Stim1 (101707184), domestic guinea pig Stim1 (100728201), Domestic Rabbit STIM1 (100345564), sheep STIM1 (101116424), cow STIM1 (534816), chicken STIM1 (419082) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(6786) Summary: This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. Mutations in this gene are associated with fatal classic Kaposi sarcoma, immunodeficiency due to defects in store-operated calcium entry (SOCE) in fibroblasts, ectodermal dysplasia and tubular aggregate myopathy. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), with the 3' end of this gene situated 1.6 kb from the 5' end of the RRM1 gene. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]
- Mouse(20866) stromal interaction molecule 1
- Rat(361618) stromal interaction molecule 1
- dog(608643) stromal interaction molecule 1
- naked mole-rat(101707184) stromal interaction molecule 1
- domestic guinea pig(100728201) stromal interaction molecule 1
- Domestic Rabbit(100345564) stromal interaction molecule 1
- sheep(101116424) stromal interaction molecule 1
- cow(534816) stromal interaction molecule 1
- chicken(419082) stromal interaction molecule 1
- Horse(100053079) stromal interaction molecule 1
- domestic cat(101087780) stromal interaction molecule 1
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Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-STIM1 antibody produced in mouse, clone 5A2, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Przeciwciało anty-STIM1, klon 1Z7E3, królicze monoklonalne, ,
Reaktywność gatunkowa
human, rat
Zastosowanie
western blot
Przeciwciało monoklonalne anty-STIM1produkowane u myszy, clone CDN3H4,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
western blot
Anti-STIM1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-STIM1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human, rat
Zastosowanie
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot