STRADA
STE20-related kinase adaptor alpha
Synonimy:
LYK5, NY-BR-96, PMSE, STRAD, Stlk
Gatunek:
Human STRADA (92335), Mouse Strada (72149), Rat Strada (303605), Horse STRADA (100064638), domestic cat STRADA (101095531), dog STRADA (609377), Domestic Rabbit STRADA (100348595), sheep STRADA (100302087), naked mole-rat Strada (101707102), domestic guinea pig Strada (100732268) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(92335) Summary: The protein encoded by this gene contains a STE20-like kinase domain, but lacks several residues that are critical for catalytic activity, so it is termed a 'pseudokinase'. The protein forms a heterotrimeric complex with serine/threonine kinase 11 (STK11, also known as LKB1) and the scaffolding protein calcium binding protein 39 (CAB39, also known as MO25). The protein activates STK11 leading to the phosphorylation of both proteins and excluding STK11 from the nucleus. The protein is necessary for STK11-induced G1 cell cycle arrest. A mutation in this gene has been shown to result in polyhydramnios, megalencephaly, and symptomatic epilepsy (PMSE) syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their full-length nature is not known. [provided by RefSeq, Sep 2009]
- Mouse(72149) STE20-related kinase adaptor alpha
- Rat(303605) STE20-related kinase adaptor alpha
- Horse(100064638) STE20-related kinase adaptor alpha
- domestic cat(101095531) STE20-related kinase adaptor alpha
- dog(609377) STE20-related kinase adaptor alpha
- Domestic Rabbit(100348595) STE20-related kinase adaptor alpha
- sheep(100302087) STE20-related kinase adaptor alpha
- naked mole-rat(101707102) STE20-related kinase adaptor alpha
- domestic guinea pig(100732268) STE20-related kinase adaptor alpha
- chicken(419957) STE20-related kinase adaptor alpha
- Zebrafish(334550) ste20-related kinase adaptor alpha
- cow(515024) STE20-related kinase adaptor alpha
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Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-STRADA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-STRADA antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
western blot