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Merck

TLR4

toll-like receptor 4

Synonimy:
ARMD10, CD284, TLR-4, TOLL
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(7099) Summary: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
  • Mouse(21898) toll-like receptor 4
  • Rat(29260) toll-like receptor 4
  • naked mole-rat(101715916) toll-like receptor 4
  • dog(403417) toll-like receptor 4
  • cow(281536) toll-like receptor 4
  • Horse(100066890) toll-like receptor 4
  • Domestic Rabbit(100009497) toll-like receptor 4
  • sheep(554263) toll-like receptor 4
  • Goat(100860955) toll-like receptor 4
  • domestic guinea pig(100724803) toll-like receptor 4
  • domestic cat(493698) toll-like receptor 4
  • chicken(417241) toll-like receptor 4

Custom & Knockdown Gene Products

ELISA

Numer produktu
Opis
Gatunek
Human TLR-4 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Mysz anty-TLR4 mAb (1H7), liquid, clone 1H7, Calbiochem®,
Reaktywność gatunkowa
human
Zastosowanie
ANTI-TLR4 antibody produced in mouse, clone 4B10, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
Monoclonal Anti-TLR4 antibody produced in mouse, clone 3B6, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunohistochemistry

western blot
Anti-TLR4 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunohistochemistry
Przeciwciało anty-TLR4produkowane u królików, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunofluorescence
immunohistochemistry

western blot

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human TLR4,
Gatunek
human