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TLR9

toll-like receptor 9

Synonimy:
CD289
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(54106) Summary: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response. [provided by RefSeq, Jul 2008]
  • Mouse(81897) toll-like receptor 9
  • Rat(338457) toll-like receptor 9
  • naked mole-rat(101715478) toll-like receptor 9
  • cow(282602) toll-like receptor 9
  • Horse(100009693) toll-like receptor 9
  • sheep(494547) toll-like receptor 9
  • dog(403502) toll-like receptor 9
  • Zebrafish(403128) toll-like receptor 9
  • domestic cat(493839) toll-like receptor 9
  • Goat(100860819) toll-like receptor 9

Custom & Knockdown Gene Products

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
Hydroxychloroquine sulfate, ≥98% (HPLC), powder,
Gatunek
human
Hydroxychloroquine Sulfate, Pharmaceutical Secondary Standard; Certified Reference Material,
Gatunek
human
Hydroksychlorochina, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
Hydroxychloroquine sulfate, analytical standard,
Gatunek
human
Hydroxychloroquine sulfate, British Pharmacopoeia (BP) Reference Standard,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-TLR9/CD289 Antibody, clone 2L12 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
human, monkey, mouse, primate
Zastosowanie
affinity binding assay
flow cytometry

immunohistochemistry

western blot
Anti-TLR9 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse
Zastosowanie
ELISA
immunofluorescence

immunohistochemistry

western blot
Monoclonal Anti-TLR9 antibody produced in mouse, clone 1E8, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunofluorescence

western blot
ANTI-TLR9 antibody produced in mouse, clone 2H5, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
ANTI-TLR9 antibody produced in mouse, clone 3B7, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human TLR9, RP11-330H6.5,
Gatunek
human
MISSION® esiRNA, targeting human TWF2, RP11-330H6.5,
Gatunek
human