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Merck

TNFRSF18

tumor necrosis factor receptor superfamily, member 18

Synonimy:
AITR, CD357, GITR, GITR-D
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(8784) Summary: This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]
  • Mouse(21936) tumor necrosis factor receptor superfamily, member 18
  • Rat(500598) tumor necrosis factor receptor superfamily, member 18
  • sheep(101108672) tumor necrosis factor receptor superfamily, member 18
  • domestic cat(101083251) tumor necrosis factor receptor superfamily, member 18
  • domestic guinea pig(100715459) tumor necrosis factor receptor superfamily, member 18
  • naked mole-rat(101715065) tumor necrosis factor receptor superfamily, member 18
  • cow(516256) tumor necrosis factor receptor superfamily, member 18
  • dog(606971) tumor necrosis factor receptor superfamily, member 18
  • Zebrafish(571217) tumor necrosis factor receptor superfamily, member 18
  • chicken(419424) tumor necrosis factor receptor superfamily, member 18

Custom & Knockdown Gene Products

ELISA

Numer produktu
Opis
Gatunek
Human GITR / TNFRSF18 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Gatunek
human
Human GITR / TNFRSF18 ELISA Kit, for cell and tissue lysates,
Gatunek
human
Mouse Tnfrsf18 ELISA Kit, ,
Gatunek
mouse

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-TNFRSF18 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL7787, purified immunoglobulin, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Przeciwciało anty-TNFRSF18 (forma rozpuszczalna), klon T10P2H9*B9, clone T10P2H9*B9, from mouse,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot
Przeciwciało anty-hGITR, klon 108-17, clone 108-17, from mouse,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
western blot

Proteins

Numer produktu
Opis
Gatunek
CD40, FC Fusion, recombinant, expressed in HEK 293 cells,
Gatunek
human