TRAF1
TNF receptor-associated factor 1
Synonimy:
EBI6, MGC:10353
Gatunek:
Human TRAF1 (7185), Mouse Traf1 (22029), Rat Traf1 (687813), cow TRAF1 (540944), dog TRAF1 (612709), chicken TRAF1 (417123), Zebrafish traf1 (100148503), naked mole-rat Traf1 (101710804), domestic guinea pig Traf1 (100723139), sheep TRAF1 (101122077) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(7185) Summary: The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins; this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
- Mouse(22029) TNF receptor-associated factor 1
- Rat(687813) TNF receptor-associated factor 1
- cow(540944) TNF receptor-associated factor 1
- dog(612709) TNF receptor-associated factor 1
- chicken(417123) TNF receptor-associated factor 1
- Zebrafish(100148503) TNF receptor-associated factor 1
- naked mole-rat(101710804) TNF receptor-associated factor 1
- domestic guinea pig(100723139) TNF receptor-associated factor 1
- sheep(101122077) TNF receptor-associated factor 1
- Domestic Rabbit(100338847) TNF receptor-associated factor 1
- domestic cat(101087620) TNF receptor-associated factor 1
- Horse(100067681) TNF receptor-associated factor 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-TRAF1 antibody produced in mouse, clone 1A6, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-TRAF1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot
western blot
Przeciwciało anty-TRAF1, klon 1F3, clone 1F3, from rat,
Reaktywność gatunkowa
human, monkey
Zastosowanie
flow cytometry
immunohistochemistry
western blot
immunohistochemistry
western blot