UMPS
uridine monophosphate synthetase
Synonimy:
OPRT
Gatunek:
Human UMPS (7372), Mouse Umps (22247), Rat Umps (288051), domestic cat UMPS (101095364), naked mole-rat Umps (101699019), dog UMPS (478593), cow UMPS (281568), sheep UMPS (780512), sheep UMPS (101116528), Zebrafish umps (393143) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(7372) Summary: This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
- Mouse(22247) uridine monophosphate synthetase
- Rat(288051) uridine monophosphate synthetase
- domestic cat(101095364) uridine monophosphate synthetase
- naked mole-rat(101699019) uridine monophosphate synthetase
- dog(478593) uridine monophosphate synthetase
- cow(281568) uridine monophosphate synthetase
- sheep(780512) uridine monophosphate synthetase
- sheep(101116528) uridine monophosphate synthetase
- Zebrafish(393143) uridine monophosphate synthetase
- chicken(424256) uridine monophosphate synthetase
- domestic guinea pig(100726089) uridine monophosphate synthetase
- Horse(100070386) uridine monophosphate synthetase
- Domestic Rabbit(100353794) uridine monophosphate synthetase
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Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-UMPS antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-UMPS antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
western blot
Monoclonal Anti-UMPS antibody produced in mouse, clone 2F5, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunofluorescence
western blot
immunofluorescence
western blot