Merck
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AP130P

Sigma-Aldrich

Goat Anti-Mouse IgG & IgM Antibody, HRP conjugate

0.8 mg/mL, Chemicon®

eCl@ss:
32160702
NACRES:
NA.46

pochodzenie biologiczne

goat

Poziom jakości

100

białko sprzężone

peroxidase conjugate

forma przeciwciała

F(ab′)2 fragment of affinity isolated antibody

antibody product type

secondary antibodies

klon

polyclonal

species reactivity

mouse

manufacturer/tradename

Chemicon®

stężenie

0.8 mg/mL

technique(s)

ELISA: suitable
western blot: suitable

transport

wet ice

Related Categories

Opis ogólny

Immunoglobulin G (IgG) is the most abundant immunoglobulin in the human serum. IgM constitutes 5-10% of total serum immunoglobulins. These immunoglobulins comprise four polypeptide chains with two heavy (H) chains and two light (L) chains. These polypeptide chains are inter-linked by disulfide bonds. IgM is a highly conserved antibody in vertebrates. IgM exists as a pentamer. Both IgG and IgM are secreted by B cells.

Zastosowanie

Goat Anti-Mouse IgG & IgM Antibody, HRP conjugate has been used in western blotting(1:400) and immunofluorescence (1:500)

Działania biochem./fizjol.

IgG facilitates antibody-dependent cell-mediated cytotoxicity (ADCC). It also aids in the activation of the classical pathway of the complement system. IgG neutralizes virus particles and toxins. IgM, an antibody that is expressed early during an immune response, aids in engulfing apoptotic cells. It exhibits polyreactive and autoreactive functionality. IgM induces tissue homeostasis by mediating the clearance of tissue-based molecules. Lower levels of IgM in serum are associated with increased autoimmune response and a higher risk of developing infections.

Informacje prawne

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Kod klasy składowania

13 - Non Combustible Solids

WGK

WGK 3

Temperatura zapłonu °F

Not applicable

Temperatura zapłonu °C

Not applicable

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