A0420000

Aminocaproic acid

European Pharmacopoeia (EP) Reference Standard

Synonim(y):
ε-Aminocaproic acid, EACA, 6-Aminocaproic acid, 6-Aminohexanoic acid
Wzór liniowy:
H2N(CH2)5CO2H
Numer CAS:
Masa cząsteczkowa:
131.17
Beilstein/REAXYS Number:
906872
Numer MDL:
Identyfikator substancji w PubChem:
NACRES:
NA.24

klasa czystości

pharmaceutical primary standard

formularz

neat

manufacturer/tradename

EDQM

mp

207-209 °C (dec.) (lit.)

Wyróżniony przemysł

Pharmaceutical (small molecule)

format

neat

temp. przechowywania

2-8°C

SMILES string

NCCCCCC(O)=O

InChI

1S/C6H13NO2/c7-5-3-1-2-4-6(8)9/h1-5,7H2,(H,8,9)

InChI key

SLXKOJJOQWFEFD-UHFFFAOYSA-N

Gene Information

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Opis ogólny

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Działania biochem./fizjol.

Lysine analog. Promotes rapid dissociation of plasmin, thereby inhibiting the activation of plasminogen and subsequent fibrinolysis. Reported to inhibit plasminogen binding to activated platelets. An early report indicated that it inhibits the activation of the first component of the complement system. Binds and inactivates Carboxypeptidase B.

Opakowanie

Unit quantity: 50 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Przestroga

Inne uwagi

Sales restrictions may apply.

storage_class_code

13 - Non Combustible Solids

WGK Germany

WGK 2

Temperatura zapłonu °F

Not applicable

Temperatura zapłonu °C

Not applicable

Certyfikat analizy

Świadectwo pochodzenia

Allergic contact dermatitis due to epsilon-aminocaproic acid: a case report and mini-review of the published work.
Yuriko Yamamoto et al.
The Journal of dermatology, 40(4), 301-303 (2013-02-13)
O N Lucas et al.
Oral surgery, oral medicine, and oral pathology, 51(2), 115-120 (1981-02-01)
On the basis of our review of the literature, it can be concluded that the advantages of E-A.C.A. include (1) safe execution of oral surgical procedures in persons with hemophilia of varying degrees of severity, (2) decrease or total elimination...
G Manjunath et al.
Clinical nephrology, 58(1), 63-67 (2002-07-27)
Epsilon-aminocaproic acid (EACA) is a potent anti-fibrinolytic agent that is used in the treatment of excessive bleeding resulting from a systemic fibrinolytic state. It can also be used to treat hematuria through its action on decreasing urinary fibrinolysis. A broad...
Blood-sparing drugs: aprotinin, tranexamic acid, and epsilon-aminocaproic acid.
D Royston
International anesthesiology clinics, 33(1), 155-179 (1995-01-01)
Are antifibrinolytic agents effective in the treatment of aneurysmal subarachnoid hemorrhage?
Travis R Eastin et al.
Annals of emergency medicine, 64(6), 658-659 (2014-06-24)

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