C3350000

Cytarabine

European Pharmacopoeia (EP) Reference Standard

• Synonym(s): Cytosine β-D-arabinofuranoside, (β-D-Arabinofuranosyl)cytosine, Ara-C, Arabinocytidine, Arabinosylcytosine, Cytarabine, Cytosine arabinoside
• Empirical Formula (Hill Notation): C₉H₁₃N₃O₅
• CAS Number: 147-94-4
• Molecular Weight: 243.22
• Beilstein: 89175
• Numer MDL: MFCD00066487
• Identyfikator substancji w PubChem: 329775037
• NACRES: NA.24

Properties

• klasa czystości: pharmaceutical primary standard
• manufacturer/tradename: EDQM
• application(s): pharmaceutical (small molecule)
• format: neat
• temp. przechowywania: 2-8°C
• SMILES string: NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O
• InChI: 1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7+,8-/m1/s1
• InChI key: UHDGCWIWMRVCDJ-CCXZUQQUSA-N
• Gene Information: human ... POLA1(5422) , POLA2(23649) , POLD1(5424) , POLD2(5425) , POLD3(10714) , POLD4(57804) , POLE(5426) , POLE2(5427) , POLE3(54107) , PRIM1(5557) , PRIM2(5558)

Description

Opis ogólny

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Działania biochem./fizjol.

Ara-C incorporates into DNA and inhibits DNA replication by forming cleavage complexes with topoisomerase I resulting in DNA fragmentation; does not inhibit RNA synthesis. Anti-leukemia agent.

Opakowanie

Unit quantity: 150 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Przestroga

Please find SDS provided by EDQM here..

Inne uwagi

Sales restrictions may apply.

Safety Information

• piktogramy: GHS07,GHS08
• Hasło ostrzegawcze: Warning
• Zwroty wskazujące rodzaj zagrożenia: H317 - H361fd
• Zwroty wskazujące środki ostrożności: P202 - P261 - P272 - P280 - P302 + P352 - P308 + P313
• Klasyfikacja zagrożeń: Repr. 2 - Skin Sens. 1
• Kod klasy składowania: 11 - Combustible Solids
• WGK: WGK 3