Merck
Wszystkie zdjęcia(2)

Dokumenty

PHG0001

SAFC

HEPES

Wszystkie zdjęcia(2)
Synonim(y):
4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid, N-(2-Hydroxyethyl)piperazine-N′-(2-ethanesulfonic acid)
Empirical Formula (Hill Notation):
C8H18N2O4S
Numer CAS:
7365-45-9
Masa cząsteczkowa:
238.30
Beilstein:
883043
Numer EC:
230-907-9
Numer MDL:
MFCD00006158
NACRES:
NA.21

pochodzenie biologiczne

synthetic

Poziom jakości

400

forma

powder

technique(s)

cell culture | mammalian: suitable

zanieczyszczenia

Endotoxin, microbial, and trace metals; tested

pH

4.7-5.3 (, )

useful pH range

6.8-8.2

pKa (25°C)

7.5

przydatność

suitable for manufacturing use

obecność zanieczyszczeń

Cytotoxicity, DNase, NICKase, RNase, and Protease; tested

SMILES string

OCCN1CCN(CC1)CCS(O)(=O)=O

InChI

1S/C8H18N2O4S/c11-7-5-9-1-3-10(4-2-9)6-8-15(12,13)14/h11H,1-8H2,(H,12,13,14)

InChI key

JKMHFZQWWAIEOD-UHFFFAOYSA-N

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Ta pozycja
H4034H6147H3375
HEPES

SAFC

PHG0001

HEPES

HEPES BioPerformance Certified, ≥99.5% (titration), suitable for cell culture

Sigma-Aldrich

H4034

HEPES

HEPES BioXtra, suitable for mouse embryo cell culture, ≥99.5% (titration)

Sigma-Aldrich

H6147

HEPES

HEPES ≥99.5% (titration)

Sigma-Aldrich

H3375

HEPES

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | embryo: suitable

technique(s)

cell culture | mammalian: suitable

impurities

Endotoxin, microbial, and trace metals; tested

impurities

endotoxin and total aerobic microbial count, tested

impurities

-

impurities

-

pH

4.7-5.3 (, )

pH

-

pH

5.0-6.5 (25 °C, 238 g/L)

pH

5.0-6.5 (25 °C, 238 g/L)

suitability

suitable for manufacturing use

suitability

-

suitability

-

suitability

-

foreign activity

Cytotoxicity, DNase, NICKase, RNase, and Protease; tested

foreign activity

DNase, RNase, NICKase, protease, none detected

foreign activity

-

foreign activity

-

Opis ogólny

Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step.

Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

Zastosowanie

HEPES is a biological buffer often referred to as a “Good′s” buffer. It is the most commonly used biological buffer since the pKa of HEPES is 7.31 which corresponds to the physiological pH of 7.36. HEPES is considered to be non-toxic to culture cell lines, highly water soluble and provides high solution clarity.

HEPES is used in cell culture media, in biopharma buffer formulations (both upstream and downstream), and in diagnostic reagents. HEPES based buffers are used in purification bioprocesses of antibodies, bioactives, proteins and growth factors.

Informacje prawne

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Kod klasy składowania

13 - Non Combustible Solids

WGK

WGK 1

Temperatura zapłonu °F

Not applicable

Temperatura zapłonu °C

Not applicable

Certificates of Analysis (COA)

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Przykład

T1503
Numer produktu
-
25G
Wielkość opakowania/ilość

Przykłady dodatkowe:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

wpisz jako1.000309185)

Problemy? Prosimy o kontakt Pomoc techniczna dla wsparcia

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Produkty Aldrich

  • Jeśli znajdziesz numer partii taki jak TO09019TO, wprowadź numer partii 09019TO bez pierwszych dwóch liter.

  • Jeśli znajdziesz numer partii z kodem wypełnienia takim jak 05427ES-021, wprowadź numer partii 05427ES bez kodu wypełnienia -021.

  • Jeśli znajdziesz numer partii z kodem wypełnienia takim jak STBB0728K9, wprowadź numer partii STBB0728 bez kodu wypełnienia K9.

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HEPES solution 1 M, pH 7.0-7.6, sterile-filtered, BioReagent, suitable for cell culture

Sigma-Aldrich

H0887

HEPES solution

HEPES sodium salt BioPerformance Certified, suitable for cell culture, ≥99.0%

Sigma-Aldrich

H3784

HEPES sodium salt

HEPES buffer solution 1 M in H2O

Sigma-Aldrich

83264

HEPES buffer solution

HEPES sodium salt ≥99.0% (titration)

Sigma-Aldrich

H7006

HEPES sodium salt

HEPES solution BioPerformance Certified, 1 M, suitable for cell culture, 0.2 μm filtered

Sigma-Aldrich

H3537

HEPES solution

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Estrogen receptor β (ERβ) is emerging as a critical factor in understanding prostate cancer biology. Although reduced in prostate cancer above Gleason grade 3, ERβ is a potential drug target at the initial stage of the disease. In human prostate
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Alexandre Albanese et al.
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A nanoparticle's physical and chemical properties at the time of cell contact will determine the ensuing cellular response. Aggregation and the formation of a protein corona in the extracellular environment will alter nanoparticle size, shape, and surface properties, giving it
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