RES6003H-B7

HEPES

• Synonym(s): 4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid, N-(2-Hydroxyethyl)piperazine-N′-(2-ethanesulfonic acid)
• Empirical Formula (Hill Notation): C₈H₁₈N₂O₄S
• CAS Number: 7365-45-9
• Molecular Weight: 238.30
• Beilstein: 883043
• Numer EC: 230-907-9
• Numer MDL: MFCD00006158
• NACRES: NA.21

Properties

• pochodzenie biologiczne: synthetic
• Poziom jakości: 400
• forma: powder
• technique(s): cell culture | mammalian: suitable
• zanieczyszczenia: Endotoxin, microbial, and trace metals; tested
• pH: 4.7-5.3 (, )
• useful pH range: 6.8-8.2
• pKa (25°C): 7.5
• przydatność: suitable for manufacturing use
• obecność zanieczyszczeń: Cytotoxicity, DNase, NICKase, RNase, and Protease; tested
• SMILES string: OCCN1CCN(CC1)CCS(O)(=O)=O
• InChI: 1S/C8H18N2O4S/c11-7-5-9-1-3-10(4-2-9)6-8-15(12,13)14/h11H,1-8H2,(H,12,13,14)
• InChI key: JKMHFZQWWAIEOD-UHFFFAOYSA-N

Description

Opis ogólny

Our SAFC^® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step.

Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

Zastosowanie

HEPES is a biological buffer often referred to as a “Good′s” buffer. It is the most commonly used biological buffer since the pKa of HEPES is 7.31 which corresponds to the physiological pH of 7.36. HEPES is considered to be non-toxic to culture cell lines, highly water soluble and provides high-solution clarity.

HEPES is used in cell culture media, biopharmaceutical buffer formulations (both upstream and downstream) and diagnostic reagents. HEPES based buffers are used in purification bioprocesses of antibodies, bioactives, proteins and growth factors.

Opakowanie

This product is available in the following package sizes:
RES6003H-B701X: 100g container
RES6003H-B703X: 5kg container
RES6003H-B705X: 25kg container
RES6003H-B706X: 50kg container

Informacje prawne

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Kod klasy składowania: 13 - Non Combustible Solids
• WGK: WGK 1
• Temperatura zapłonu °F: Not applicable
• Temperatura zapłonu °C: Not applicable