Chemoresistance is associated with increased cytoprotective autophagy and diminished apoptosis in bladder cancer cells treated with the BH3 mimetic (-)-Gossypol (AT-101).
BMC Cancer, 15, 224-224 (2015)
Soft drug-resistant ovarian cancer cells invade via two distinct mechanisms utilizing myosin IIB
Nature, 099655-099655 (2017)
Efficacy of adjuvant chemotherapy for non-small cell lung cancer assessed by metastatic potential associated with ACTN4.
Deepak Parashar et al.
Cancer research, 80(24), 5554-5568 (2020-10-23)
Peritoneal spread is the primary mechanism of metastasis of ovarian cancer, and survival of ovarian cancer cells in the peritoneal cavity as nonadherent spheroids and their adherence to the mesothelium of distant organs lead to cancer progression, metastasis, and mortality....
Taeshin Kim et al.
Endocrinology, 160(11), 2543-2555 (2019-09-11)
A defining characteristic of the hypothalamus-pituitary-gonad reproductive endocrine axis is the episodic secretion of the pituitary gonadotropin hormones LH and FSH by the anterior pituitary gonadotropes. Hormone secretion is dictated by pulsatile stimulation, with GnRH released by hypothalamic neurons that...