We offer an unparalleled portfolio of natural and unnatural amino acids, resins, and coupling reagents of unrivaled quality for peptide synthesis, including the entire portfolio of over 1,000 Novabiochem® products. Combining this extensive offering with the latest innovative products such as the phophoroserine building block, Fmoc-Ser(PO(NHiPr)2)-OH), Trp-BODIPY fluorescent probe, CITC coupling reagent, and the Pinc cyclization reagent we’ll make your breakthroughs feel closer than ever. Many products are supported by detailed protocols, application examples, and practical advice. Moreover, the famous Novabiochem application notes are now available online!
For years, Novabiochem® peptide synthesis reagents have set the gold standard for quality and reliability. The quality of reagents is critical to the scientific credibility of results obtained with synthetic peptides. Small, almost trivial, differences in purity of the starting reagents can greatly affect the microheterogeneity of the product peptide. For example, building blocks with only 99.5% optical purity can theoretically only produce 78% of the target 50mer, whereas building blocks with 99.8% optical purity rise to 90%. The purified products from both syntheses can look homogeneous by HPLC, however the peptide obtained using the 99.5% optically pure building blocks will only contain at maximum 78% of the target: the diastereomeric by-products will be hiding under the product peak as they are inseparable and are of course undetectable by MS.
It is for this reason we strive to make our 20 standard Fmoc-amino acids amongst the highest quality available on the market. Most importantly, we analyze for known microimpurities, which could produce inseparable and undetectable impurities in the final peptide product:
With the capability to offer large batches, we support your growth every step of the way, from R&D to scaled-up production across the globe. Get the exact quality and quantity you need for: