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Chang-Gui Pan et al.
Chemosphere, 114, 16-25 (2014-08-13)
A survey on contamination profiles of eighteen perfluoroalkyl substances (PFASs) was performed via high performance liquid chromatography-tandem mass spectrometry for surface water and sediments from five typical rivers of the Pearl River Delta region, South China in summer and winter
Yichen Wang et al.
Environmental science & technology, 49(10), 6294-6303 (2015-04-16)
Perfluorooctane sulfate (PFOS), a persistent organic pollutant, has recently been closely linked with an increased risk of tumorigenesis. However, PFOS has yielded negative results in various tests of genotoxicity. The present study aimed to investigate the mutagenic response to PFOS
Anne P Starling et al.
Environment international, 62, 104-112 (2013-11-06)
Perfluoroalkyl substances (PFASs) are widespread and persistent environmental pollutants. Previous studies, primarily among non-pregnant individuals, suggest positive associations between PFAS levels and certain blood lipids. If there is a causal link between PFAS concentrations and elevated lipids during pregnancy, this
Julian Campo et al.
The Science of the total environment, 503-504, 48-57 (2014-06-18)
The occurrence and sources of 21 perfluoroalkyl substances (PFASs: C4-C14, C16, C18 carboxylate, C4, C6-C8 and C10 sulfonates and C8 sulfonamide) were determined in water, sediment, and biota of the Llobregat River basin (NE Spain). Analytes were extracted by solid
Jingguang Li et al.
Environment international, 53, 47-52 (2013-01-17)
Because of the disadvantages of invasive sampling, it is desirable to explore non-invasive matrices for human biomonitoring of perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA). The aim of this study was to evaluate the application of nail, hair and urine
Hin-Ting Wan et al.
Endocrinology, 155(1), 249-262 (2013-10-31)
Environmental toxicants such as perfluorooctanesulfonate (PFOS) have been implicated in male reproductive dysfunction, including reduced sperm count and semen quality, in humans. However, the underlying mechanism(s) remains unknown. Herein PFOS at 10-20 μM (∼5-10 μg/mL) was found to be more
L Bastos Sales et al.
Toxicology in vitro : an international journal published in association with BIBRA, 27(6), 1634-1643 (2013-04-23)
Recent studies suggest that endocrine disrupting chemicals (EDCs) may form a risk factor for obesity by altering energy metabolism through epigenetic gene regulation. The goal of this study is to investigate the effects of a range of EDCs with putative
Yaning Fu et al.
Chemosphere, 110, 104-110 (2014-03-19)
133 Serum samples collected from Henan donors aged from 0 to 88years were analyzed for 12 perfluorinated compounds (PFCs). Perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) accounted for 69.19% of the total PFCs in serum samples, with a median concentration
Yu Wang et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 76, 70-76 (2014-12-20)
The present study aims to explore the effects of perfluorooctane sulfonate (PFOS) on cognitive function in developing rats and the underlying mechanism associated with synaptic plasticity. Pregnant Wistar rats were fed with 0, 5, and 15 mg/L of PFOS via drinking
Natasha D White et al.
The Science of the total environment, 521-522, 79-89 (2015-04-02)
Urban areas are sources of perfluoroalkyl substances (PFASs) in the environment, although little is known about specific point sources and distribution of PFASs. Sentinel species, like bottlenose dolphins, are important indicators of environmental perturbations. The high PFAS levels found in
Yan Long et al.
PloS one, 8(1), e54176-e54176 (2013-02-06)
Perfluorooctane sulfonate (PFOS) is a ubiquitous pollutant and found in the environment and in biota. The neurotoxicity of PFOS has received much concern among its various toxic effects when given during developing period of brain. However, little is known about
S Squadrone et al.
Environmental monitoring and assessment, 187(7), 438-438 (2015-06-19)
Perfluoroalkylated substances (PFASs) are highly fluorinated aliphatic compounds with high thermal and chemical stability, used in a range of industrial applications. Extensive screening analyses in biota samples from all over the world have shown the bioaccumulation of PFAS into higher
M Kummu et al.
Placenta, 36(10), 1185-1191 (2015-08-26)
Perfluorinated alkyl acids (PFAAs) are widely used in industry and consumer products. Pregnant women are exposed to PFAAs and their presence in umbilical cord blood represents fetal exposure. Interestingly, PFAAs are substrates for organic anion transporters (OAT) of which OAT4
E D van Asselt et al.
Food chemistry, 141(2), 1489-1495 (2013-06-26)
Dietary intake is the predominant route for human exposure to perfluorooctane sulfonic acid (PFOS). Single pollution events may thus affect human exposure if polluted ground and water is used to produce animal feed or food. In this study, a physiologically
Jeonghoon Han et al.
Aquatic toxicology (Amsterdam, Netherlands), 165, 136-143 (2015-06-04)
2,2',4,4'-tetrabromodiphenyl ether (BDE-47) and perfluorooctane sulfonate (PFOS) are widely dispersed persistent organic pollutants (POPs) in the marine ecosystem. However, their toxic effects on marine organisms are still poorly understood. In this study, we investigated the effects of BDE-47 and PFOS
A L Brantsæter et al.
Environment international, 54, 74-84 (2013-02-20)
Perfluoroalkyl substances (PFASs) are widespread pollutants that have been associated with adverse health effects although not on a consistent basis. Diet has been considered the main source of exposure. The aim of the present study was to identify determinants of
Eva Gorrochategui et al.
Environmental science and pollution research international, 21(20), 11907-11916 (2014-06-28)
The aim of this study was to develop a method based on ultra high performance liquid chromatography coupled with mass spectrometry (UHPLC-MS) for lipid profiling in human placental choriocarcinoma (JEG-3) cells. Lipids were solid-liquid extracted from JEG-3 cells using a
Ayla Çelik et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 53, 249-255 (2012-12-19)
Perfluorooctane sulfonate (PFOS) is a man-made fluorosurfactant and global pollutant. PFOS a persistent and bioaccumulative compound, is widely distributed in humans and wildlife. Therefore, it was added to Annex B of the Stockholm Convention on Persistent Organic Pollutants in May
Veerle L B Jaspers et al.
Environment international, 52, 9-16 (2012-12-26)
Perfluoroalkyl substances (PFASs) were investigated in tail feathers and soft tissues (liver, muscle, preen gland and adipose tissue) of barn owl (Tyto alba) road-kill victims (n=15) collected in the province of Antwerp (Belgium). A major PFAS producing facility is located
Yifeng Zhang et al.
Environment international, 53, 9-17 (2013-01-15)
The sources and pathways of human exposure to perfluoroalkyl acids (PFAAs) are not well characterized, particularly in China where many perfluorinated substances are now manufactured. Here, isomer-specific PFAA analysis was used for the first time to evaluate exposure sources for
Lilan Zhang et al.
Chemosphere, 114, 114-120 (2014-08-13)
Rotifers play an important role in the dynamics of freshwater and coastal marine ecosystems, and are also important tools for assessing toxicity in aquatic environments. In this study, the effects of perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) on the
Ulla Nordström Joensen et al.
Human reproduction (Oxford, England), 28(3), 599-608 (2012-12-20)
Is exposure to perfluorinated compounds (PFCs) associated with testicular function (reproductive hormone levels and semen quality) in healthy men? PFOS levels were significantly negatively associated with serum testosterone (total and calculated free), but not with any other reproductive hormones or
Piw Das et al.
Environmental science and pollution research international, 22(12), 8902-8910 (2013-05-23)
Aqueous film-forming foams (AFFF) are used to extinguish hydrocarbon fuel fires. Certain AFFF products such as 3M Lightwater contain perfluorooctane sulfonate (PFOS) as the active ingredient which is highly persistent in the environment and is thus globally prevalent. With thousands
Clara Amalie G Timmermann et al.
The Journal of clinical endocrinology and metabolism, 99(4), E608-E614 (2014-03-13)
Our objective was to explore whether childhood exposure to perfluorinated and polyfluorinated compounds (PFCs), widely used stain- and grease-repellent chemicals, is associated with adiposity and markers of glycemic control. Body mass index, skinfold thickness, waist circumference, leptin, adiponectin, insulin, glucose
Shuangwei Xie et al.
Environment international, 52, 1-8 (2012-12-26)
Perfluorooctane sulfonate (PFOS) and related chemicals (collectively "PFOS equivalents") are currently manufactured and used in a wide variety of industrial processes in China. Since 2003, the national annual production has increased dramatically to accommodate both domestic demands and ongoing overseas
Ram B Jain
Journal of toxicology and environmental health. Part A, 76(7), 409-421 (2013-04-25)
The presence of perfluoroalkyl chemicals (PFC) in maternal serum may pose a risk to the developing fetus. A large-scale study to evaluate the extent of exposure to PFC in pregnant and nonpregnant females in the United States has not been
Ziquan Lv et al.
Environmental toxicology, 28(9), 532-542 (2013-08-29)
Perfluorooctane sulfonate (PFOS), which belongs to the degradation product of many perfluorinated compounds, is on the list of persistent organic pollutants (POPs) and is currently detected in both wildlife and humans. The consequence of gestational and lactational exposure to PFOS
Kathleen Roland et al.
Aquatic toxicology (Amsterdam, Netherlands), 128-129, 43-52 (2012-12-25)
Since the 1980s, the stocks of European eel have been declining in most of their geographical distribution area. Many factors can be attributed to this decline such as pollution by xenobiotics like perfluorooctane sulfonate (PFOS). This study aimed at evaluating
Nanyang Yu et al.
Environmental science & technology, 47(2), 710-717 (2012-12-21)
The spatial distribution of 10 perfluoroalkyl acids including linear and branched (six monotrifluoromethyl isomers) perfluorooctane sulfonate (PFOS) in surface water was investigated in Huai River Basin and Taihu Lake in Jiangsu Province, China. In the water samples from Huai River
Trine Reistad et al.
Toxicology letters, 218(1), 56-60 (2013-01-24)
The present communication investigates the effects of different perfluoroalkylated compounds (PFCs) on formation of reactive oxygen species (ROS) and cell death in cultured cerebellar granule cells. This allows direct comparison with similar effects found for other environmental contaminants like polychlorinated
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