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Henrik Viberg et al.
Toxicology, 304, 185-191 (2013-01-05)
Perfluoroalkyl acids, including perfluorohexane sulfonate (PFHxS), are fluorinated organic compounds used as surfactants and water and stain repellents in carpets, paper, and textiles, with characteristics to bioaccumulate and biomagnify in the food chain. PFHxS is found in umbilical cord blood...
Elena De Felip et al.
Chemosphere, 137, 1-8 (2015-05-13)
Perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) concentrations were determined in serum samples collected in 2011-2012 from 549 nulliparous Italian women of reproductive age who resided in six different Italian Regions. Assessment of exposure to perfluorinated compounds was part of...
Kirsten T Eriksen et al.
PloS one, 8(2), e56969-e56969 (2013-02-27)
Perfluorooctanoate (PFOA) and perfluorooctane sulfonate (PFOS) are used in a variety of consumer products and have been detected worldwide in human blood. Recent studies mainly of highly exposed populations have indicated that PFOA and PFOS may affect serum cholesterol levels...
Yifeng Zhang et al.
Environment international, 68, 185-191 (2014-04-22)
A total of 100 serum samples from 50 new couples (none of the females in this study has ever been pregnant) in Tianjin, North China, were analyzed for eleven perfluoroalkyl acids (PFAAs) with isomer-specific method. Among all samples, total perfluorooctanesulfonate...
Cathrine Carlsen Bach et al.
Environmental health : a global access science source, 14, 59-59 (2015-07-08)
We previously demonstrated an association between plasma perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) and longer time to pregnancy (TTP) in a sample from the Danish National Birth Cohort (DNBC, 1996-2002). In this study we investigated this association in a new...
Ana R Ribeiro et al.
Journal of chromatography. A, 1418, 140-149 (2015-10-04)
The fate and removal of organic micropollutants in the environment is a demanding issue evidenced by the recent European policy. This work presents an analytical method for the trace quantification of 37 micropollutants including Priority Substances (Directive 2013/39/EU), substances of...
Eva Gorrochategui et al.
Analytica chimica acta, 854, 20-33 (2014-12-07)
A lipidomic study was developed in a human placental choriocarcinoma cell line (JEG-3) exposed to tributyltin (TBT) and to a mixture of perfluorinated chemicals (PFCs). The method was based on the application of multivariate curve resolution-alternating least squares (MCR-ALS) to...
Fei Wang et al.
Environmental science & technology, 49(9), 5672-5680 (2015-04-09)
The mineralization of perfluorinated alkyl substances (PFASs) by calcium compounds during the waste thermal treatment was systemically studied. Different calcium compounds showed different mineralization efficiencies of PFASs during the thermal process, owing to the different reaction mechanisms. Calcium hydroxide was...
Changhui Liu et al.
Environmental toxicology and chemistry, 32(10), 2226-2233 (2013-06-15)
Perfluorinated chemicals (PFCs) are a group of compounds with varying carbon chains and functional groups. Currently, available toxicity studies of PFCs are limited mainly to dominant species. While many other PFCs are detected in the environment and biota, it is...
Parva Zareitalabad et al.
Ecotoxicology and environmental safety, 95, 39-43 (2013-06-13)
As a consequence of their widespread use, e.g. as protective coatings for fabrics, and their resistance to thermal and biological breakdown, perfluorinated compounds are increasingly found in the environment, but little is known about their ecotoxicological properties. A 40-day microcosm...
Shahid Ullah et al.
Environment international, 65, 63-72 (2014-01-29)
A method was developed for simultaneous analysis of perfluoroalkane sulfonic acids (PFSAs) and their sulfonamide-based precursors (perfluoroalkane sulfonamidoacetic acids (FASAAs), sulfonamides (FASAs), and sulfonamidoethanols (FASEs)) in fish muscle. Extraction was performed with acetonitrile followed by a clean-up and fractionation step...
Lianying Zhang et al.
Toxicology and applied pharmacology, 279(3), 275-283 (2014-07-08)
Perfluorinated compounds (PFCs) have been shown to disrupt lipid metabolism and even induce cancer in rodents through activation of peroxisome proliferator-activated receptors (PPARs). Lines of evidence showed that PPARα was activated by PFCs. However, the information on the binding interactions...
Qin-Qin Lou et al.
Ecotoxicology (London, England), 22(7), 1133-1144 (2013-08-03)
Perfluorobutanesulfonate (PFBS), as a substitute for perfluorooctanesulfonate (PFOS), is widespread in the environment and biotic samples as well as PFOS. To investigate effects of PFOS and PFBS on the growth and sexual development of amphibians, we exposed Xenopus laevis tadpoles...
Zhuyu Sun et al.
Chemosphere, 174, 127-135 (2017-02-06)
Perfluoroalkyl acids (PFAAs) have been found to be ubiquitously disseminated in the environment due to their widespread use in recent decades. In this study, the occurrence and spatiotemporal distribution of PFAAs in the surface water of Huangpu River, Shanghai, China...
Jinxia Liu et al.
Environment international, 61, 98-114 (2013-10-16)
Polyfluoroalkyl chemicals containing perfluoroalkyl moieties have been widely used in numerous industrial and commercial applications. Many polyfluoroalkyl chemicals are potential perfluoroalkyl acid (PFAA) precursors. When they are released to the environment, abiotic and microbial degradation of non-fluorinated functionalities, polyfluoroalkyl and...
Francisca Pérez et al.
Environment international, 59, 354-362 (2013-07-31)
Perfluoroalkyl substances (PFASs) are environmental pollutants with an important bioaccumulation potential. However, their metabolism and distribution in humans are not well studied. In this study, the concentrations of 21 PFASs were analyzed in 99 samples of autopsy tissues (brain, liver...
Andrew M Watkins et al.
Molecular and cellular endocrinology, 400, 90-101 (2014-12-03)
The 3T3-L1 preadipocyte culture system has been used to examine numerous compounds that influence adipocyte differentiation or function. The perfluoroalkyl acids (PFAAs), used as surfactants in a variety of industrial applications, are of concern as environmental contaminants that are detected...
Gang Pan et al.
The Science of the total environment, 487, 778-784 (2013-12-12)
The distribution in water and sediment, the sources/sinks and the risk of perfluorinated compounds (PFCs) in Lake Taihu, China were investigated. The total PFCs concentration was 164 to 299 ng L(-1) in water and 5.8 to 35 ng g(-1) (dw)...
Huai-Cai Zeng et al.
Environmental toxicology, 30(9), 1082-1090 (2014-03-13)
Perfluorooctanyl sulfonate (PFOS), a cardiac toxicity compound, has been widely detected in the environment and in organisms. However, the toxic mechanism is not clear. Our previous study indicated that prenatal PFOS exposure led to swollen mitochondrial with vacuolar structure and...
Jiangfei Chen et al.
Aquatic toxicology (Amsterdam, Netherlands), 150, 124-132 (2014-03-29)
As a persistent organic contaminant, perfluorooctanesulphonic acid (PFOS) has been widely detected in the environment, wildlife, and humans. The present study revealed that zebrafish embryos exposed to 16 μM PFOS during a sensitive window of 48-96 hour post-fertilization (hpf) disrupted...
Anders Galatius et al.
Environmental science and pollution research international, 20(11), 8013-8020 (2013-03-28)
Profiles of seven compounds of perfluoro-alkyl substances (PFASs) were compared among three species of top predators from the Danish North Sea: the white-beaked dolphin (Lagenorhynchus albirostris), the harbor porpoise (Phocoena phocoena), and the harbor seal (Phoca vitulina). The seals had...
Beth Javins et al.
Environmental science & technology, 47(3), 1606-1613 (2013-01-01)
Perfluoroalkyl substances are manmade chemicals used in many consumer products and have become ubiquitous in the environment. Animal studies and a limited number of human studies have demonstrated developmental effects in offspring exposed to perfluoroalkyl substances in utero, but the...
Ha Thi Ngo et al.
Environmental research, 132, 251-263 (2014-05-20)
We examined whether perfluorooctanoate (PFOA) or perfluorooctane sulfonate (PFOS) had obesogenic effects and if they increased spontaneous intestinal tumorigenesis in the mouse model C57BL/6J-Min/+ (multiple intestinal neoplasia) after in utero exposure. The dams were exposed to PFOA or PFOS (0.01...
Sarah Dee Geiger et al.
American journal of epidemiology, 177(11), 1255-1262 (2013-04-05)
Hyperuricemia in children is associated with increased risk of high blood pressure, metabolic syndrome, and future cardiovascular disease. Serum perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) levels have been shown to be positively associated with hyperuricemia in adults, but the...
Guangzhi He et al.
Journal of colloid and interface science, 405, 189-194 (2013-06-14)
The surface-associated structures and growth modes of perfluorooctane sulfonate (PFOS) at water-rutile TiO2 interfaces were defined by molecular dynamics (MD) simulations. The results showed that a compact PFOS layer was generated at the rutile surfaces, and the assembling structures and...
Jia Bao et al.
Environmental science and pollution research international, 21(12), 7650-7655 (2014-03-14)
Severe perfluoroalkyl acid (PFAA) contamination resulting from the fast-growing semiconductor, electrochemical, and optoelectronic industries has been determined in the river water in the vicinity of the Taipei area, Taiwan, during recent years. However, little is known about body burdens of...
Shuangwei Xie et al.
Environment international, 59, 336-343 (2013-07-31)
Perfluorooctane sulfonate (PFOS) and related chemicals (collectively "PFOS equivalents") have been released to the environment through widespread consumer use and disposal of PFOS-containing products like carpet, leather, textiles, paper, food containers, household cleansers, etc. Accordingly, in addition to PFOS-related industries...
Victor A Arias E et al.
Environmental monitoring and assessment, 187(1), 4111-4111 (2014-11-20)
Although the use of perfluorooctane sulfonic acid (PFOS)/perfluorooctanoic acid (PFOA)-based aqueous fire-fighting foams (AFFF) has been banned due to their persistence, bioaccumulation and toxicity to biota, PFOS and PFOA are still present at significant levels in the environment due to...
Takeo Sakurai et al.
Environmental toxicology and chemistry, 32(9), 2009-2017 (2013-05-03)
The authors investigated the kinetics of transfer of perfluorooctane sulfonate (PFOS) from water, suspended sediment, and bottom sediment to a marine benthic fish, the marbled flounder (Pseudopleuronectes yokohamae). Fish were exposed in 3 treatments to PFOS in combinations of these...
Wan Norhamidah Wan Ibrahim et al.
Toxicology and applied pharmacology, 269(1), 51-60 (2013-03-19)
Perfluorinated compounds are ubiquitous chemicals of major concern for their potential adverse effects on the human population. We have used primary rat embryonic neural stem cells (NSCs) to study the effects of perfluorooctane sulfonate (PFOS) on the process of NSC...
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