Showing 1-6 of 6 wyniki(-ów) for "EHU064501"
Chao Huang et al.
Journal of extracellular vesicles, 9(1), 1692417-1692417 (2019-12-07)
Tumour metastasis suppressor KAI1/CD82 inhibits tumour cell movement. As a transmembrane protein, tetraspanin CD82 bridges the interactions between membrane microdomains of lipid rafts and tetraspanin-enriched microdomains (TEMs). In this study, we found that CD82 and other tetraspanins contain cholesterol recognition/interaction...
Muskan Floren et al.
Oncogene, 39(19), 3910-3925 (2020-03-24)
A principal challenge in treating acute myeloid leukemia (AML) is chemotherapy refractory disease. As such, there remains a critical need to identify key regulators of chemotherapy resistance in AML. In this study, we demonstrate that the membrane scaffold, CD82, contributes...
Jianwen Long et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 102, 1195-1202 (2018-05-02)
Melanoma has been a severe threat to human health, microRNAs play vital roles in the oncogenesis and progression of cancers. In this report, the roles and mechanism of miR-338-5p were investigated in the development of melanoma. A total of 46...
Rong Zhou et al.
Acta pharmacologica Sinica, 35(11), 1375-1384 (2014-09-30)
Ryanodine receptor 2 (RyR2) is a critical component of intracellular Ca(2+) signaling in vascular smooth muscle cells (VSMCs). The aim of this study was to investigate the role of RyR2 in abnormal vascular reactivity after hemorrhagic shock in rats. SD...
Thomas B Layton et al.
Nature communications, 11(1), 2768-2768 (2020-06-04)
Fibrotic disorders are some of the most devastating and poorly treated conditions in developed nations, yet effective therapeutics are not identified for many of them. A major barrier for the identification of targets and successful clinical translation is a limited...
Qing-Hui Zhang et al.
Digestive diseases and sciences, 60(7), 1967-1976 (2015-02-06)
This study was to investigate the effects and mechanisms of miR-362-3p on regulation of gastric cancer (GC) cell metastasis potential. We detected miR-362-3p level in GC and adjacent normal tissues and investigated the relationship with clinicopathological factors. Next, we analyzed...

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