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Edyta Nalewajko-Sieliwoniuk et al.
Talanta, 133, 38-44 (2014-12-02)
The first method for the simultaneous determination of polyphenolic antioxidants in extracts from leaves of Cirsium palustre based on high performance liquid chromatography combined with flow injection chemiluminescence detection (HPLC-FI-CL) has been developed. The extracts were prepared by using methanol
Jörg Kittelmann et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 988, 98-105 (2015-03-15)
High-throughput batch screening technologies have become an important tool in downstream process development. Although continuative miniaturization saves time and sample consumption, there is yet no screening process described in the 384-well microplate format. Several processes are established in the 96-well
Sima Rahimian et al.
Biomaterials, 37, 469-477 (2014-12-03)
Particulate antigen delivery systems aimed at the induction of antigen-specific T cells form a promising approach in immunotherapy to replace pharmacokinetically unfavorable soluble antigen formulations. In this study, we developed a delivery system using the model protein antigen ovalbumin (OVA)
Danila V Zimenkov et al.
Journal of clinical microbiology, 53(4), 1103-1114 (2015-01-23)
In addition to the obligatory pathogenic species of the Mycobacterium tuberculosis complex and Mycobacterium leprae, the genus Mycobacterium also includes conditionally pathogenic species that in rare cases can lead to the development of nontuberculous mycobacterial diseases. Because tuberculosis and mycobacteriosis
Mehrorang Ghaedi et al.
Journal of chromatographic science, 53(7), 1222-1231 (2015-02-01)
A novel vortex-assisted surfactant-enhanced dispersive liquid-liquid microextraction combined with high-performance liquid chromatography (VASEDLLME-HPLC) was developed for the determination of thymol and carvacrol (phenolic compound). In this method, the extraction solvent (CHCl3) was dispersed into the aqueous samples via a vortex
Esther Tejeda-Montes et al.
Biomaterials, 35(29), 8339-8347 (2014-07-06)
The search for alternative therapies to improve bone regeneration continues to be a major challenge for the medical community. Here we report on the enhanced mineralization, osteogenesis, and in vivo bone regeneration properties of a bioactive elastin-like recombinamer (ELR) membrane.
Hiroyuki Kashima et al.
Environmental science & technology, 49(5), 3195-3202 (2015-01-28)
Alternative metabolic options of exoelectrogenic biofilms in bioelectrochemical systems (BESs) are important not only to explain the fundamental ecology and performance of these systems but also to develop reliable integrated nutrient removal strategies in BESs, which potentially involve substrates or
Daniel J O'Sullivan et al.
BMC microbiology, 15, 266-266 (2015-11-19)
The aim of this study was to employ high-throughput DNA sequencing to assess the incidence of bacteria with biogenic amine (BA; histamine and tyramine) producing potential from among 10 different cheeses varieties. To facilitate this, a diagnostic approach using degenerate
Matthew Di Rago et al.
Forensic science international, 243, 35-43 (2014-05-06)
The aim of this study was to develop an LC-MS/MS based screening technique that covers a broad range of acidic and neutral drugs and poisons by combining a small sample volume and efficient extraction technique with simple automated data processing.
James E Thornton et al.
Nucleic acids research, 42(18), 11777-11791 (2014-09-17)
Recent small RNA sequencing data has uncovered 3' end modification of mature microRNAs (miRNAs). This non-templated nucleotide addition can impact miRNA gene regulatory networks through the control of miRNA stability or by interfering with the repression of target mRNAs. The
Muneeb U Rehman et al.
Pharmacological reports : PR, 66(6), 1050-1059 (2014-12-03)
Cisplatin is an effective and extensively used chemotherapeutic agent to treat range of malignancies, but its therapeutic use is limited because of dose-dependent nephrotoxicity and hepatotoxicity. Several published reports advocate that supplementation with antioxidant can influence cisplatin induced hepatic damage.
Yang Zhang et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 960, 52-58 (2014-05-03)
A novel TiO2/diatomite composite (TD) was prepared and then characterized by scanning electron microscope (SEM) and Fourier Transform Infrared (FTIR). The results of SEM showed that after modification, the porous surface of diatomite was covered with TiO2. Both diatomite and
Ludmila Müllerová et al.
Journal of chromatography. A, 1384, 147-154 (2015-02-11)
Interactions among analyte forms that undergo simultaneous dissociation/protonation and complexation with multiple selectors take the shape of a highly interconnected multi-equilibrium scheme. This makes it difficult to express the effective mobility of the analyte in these systems, which are often
S Syama et al.
Toxicology mechanisms and methods, 24(9), 644-653 (2014-08-21)
Engineered nanoparticles are developed for various applications in industrial, electrical, agricultural, pharmaceutical and medical fields due to their unique properties. Nanoparticles such as TiO(2) and ZnO are widely used in cosmetics for UV protection. The toxicological investigations of ZnO NPs
Maren Kleine-Brueggeney et al.
Cellular signalling, 26(9), 1985-1997 (2014-05-20)
The role of naturally occurring human α1a-Adrenergic Receptor (α1aAR) genetic variants associated with cardiovascular disorders is poorly understood. Here, we present the novel findings that expression of human α1aAR-247R (247R) genetic variant in cardiomyoblasts leads to transition of cardiomyoblasts into
Mahboube Eslami Moghadam et al.
Combinatorial chemistry & high throughput screening, 17(9), 781-789 (2014-09-30)
Studies on the interactions between metallodrugs and human serum albumin (HSA), as carrier for drugs and biological molecules, are extremely important to design and discover new drugs. The interaction of three novel synthesized complexes of [Pd(phen)(R-gly)]NO3, where R-gly is methyl-
Alice Berger et al.
BMC veterinary research, 11, 282-282 (2015-11-15)
Cats with feline calicivirus (FCV)-related symptoms are commonly presented to veterinary practitioners. Various clinical manifestations have been attributed to FCV, i.e. upper respiratory tract disease (URTD), oral ulcerations, gingivostomatitis, limping syndrome and virulent systemic disease. Additionally, healthy cats can shed
Anne Bellon et al.
Transfusion, 54(4), 1028-1036 (2013-09-17)
The high resistance of prions to inactivating treatments requires the proper management of decontaminating procedures of equipment in contact with materials of human or animal origin destined for medical purposes. Sodium hydroxide (NaOH) is widely used today for this purpose
Kathirvel Gopalakrishnan et al.
Hypertension (Dallas, Tex. : 1979), 65(1), 200-210 (2014-11-12)
Long noncoding RNAs (lncRNAs) are an emerging class of genomic regulatory molecules reported in various species. In the rat, which is one of the major mammalian model organisms, discovery of lncRNAs on a genome-wide scale is lagging. Renal lncRNA sequencing
Chien-Liang Liu et al.
Small (Weinheim an der Bergstrasse, Germany), 10(19), 3962-3969 (2014-07-22)
The room-temperature, aqueous-phase synthesis of iron-oxide nanoparticles (IO NPs) with glutathione (GSH) is reported. The simple, one-step reduction involves GSH as a capping agent and tetrakis(hydroxymethyl)phosphonium chloride (THPC) as the reducing agent; GSH is an anti-oxidant that is abundant in
Yanping He et al.
Journal of microencapsulation, 31(5), 430-439 (2014-04-05)
The retention and adhesion of melamine formaldehyde (MF) microcapsules on a model fabric surface in aqueous solution were investigated using a customised flow chamber technique and atomic force microscopy (AFM). A cellulose film was employed as a model fabric surface.
Jie Xiao et al.
Journal of agricultural and food chemistry, 63(47), 10263-10270 (2015-11-06)
Kafirin nanoparticle-stabilized Pickering emulsions (KPEs) were used to encapsulate curcumin. The stability of KPEs under processing conditions and their protective effects against photo-oxidation of curcumin and lipid oxidation of oil in emulsions, as well as the digestion profiles in gastrointestinal
N G R Dayan Elshan et al.
Organic & biomolecular chemistry, 13(6), 1778-1791 (2014-12-17)
Melanocortin receptors can be used as biomarkers to detect and possibly treat melanoma. To these ends, molecules bearing one, two, or three copies of the weakly binding ligand MSH(4) were attached to scaffolds based on phloroglucinol, tripropargylamine, and 1,4,7-triazacyclononane by
Aurore Masson et al.
Scientific reports, 5, 16898-16898 (2015-11-19)
Today, Light Sheet Fluorescence Microscopy (LSFM) makes it possible to image fluorescent samples through depths of several hundreds of microns. However, LSFM also suffers from scattering, absorption and optical aberrations. Spatial variations in the refractive index inside the samples cause
Di Xu et al.
Journal of environmental sciences (China), 25(4), 637-644 (2013-08-09)
Organic phosphorus (nonreactive P, NRP) is a major component of P in sediments, but information about its chemical forms and dynamic transformation is limited. The chemical forms and dynamic behaviors of NRP in a sediment profile from Lake Taihu, a
Lillian Seu et al.
AIDS research and therapy, 11, 27-27 (2014-09-03)
The level (or frequency) of circulating monocyte subpopulations such as classical (CD14(hi)CD16(-)) and non-classical (CD14(dim)CD16(+)) monocytes varies during the course of HIV disease progression and antiretroviral therapy (ART). We hypothesized that such variation and/or differences in the degree to which
Daman Kumari et al.
Human mutation, 35(12), 1485-1494 (2014-09-17)
Fragile X syndrome (FXS) is the most frequent cause of inherited intellectual disability and autism. It is caused by the absence of the fragile X mental retardation 1 (FMR1) gene product, fragile X mental retardation protein (FMRP), an RNA-binding protein
Iara Maíra de Oliveira Viana et al.
Journal of pharmaceutical and biomedical analysis, 96, 241-248 (2014-05-02)
In this study, a simple method using microextraction by packed sorbent and high-performance liquid chromatography with ultraviolet detection for simultaneous determination of chlorpropamide, gliclazide and glimepiride in human plasma was developed and validated. A fractional factorial design and a complete
Xin Wang et al.
ACS nano, 8(12), 12151-12166 (2014-12-02)
Chemoresistance is a primary cause of treatment failure in cancer and a common property of tumor-initiating cancer stem cells. Overcoming mechanisms of chemoresistance, particularly in cancer stem cells, can markedly enhance cancer therapy and prevent recurrence and metastasis. This study
Hong-Min Meng et al.
Analytical chemistry, 86(24), 12321-12326 (2014-11-18)
Glutathione (GSH) serves vital cellular biological functions, and its abnormal levels are associated with many diseases. To better understand its physiological and pathological functions, efficient methods for monitoring of GSH in living systems are desired. Although quite a few small
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