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CACNB1

calcium channel, voltage-dependent, beta 1 subunit

Synonyms:
CAB1, CACNLB1, CCHLB1
Species:
UniProtKB ID:
Gene ID:
  • Human(782) Summary: The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(12295) calcium channel, voltage-dependent, beta 1 subunit
  • Rat(50688) calcium channel, voltage-dependent, beta 1 subunit
  • Zebrafish(436925) calcium channel, voltage-dependent, beta 1 subunit
  • cow(327703) calcium channel, voltage-dependent, beta 1 subunit
  • sheep(101122960) calcium channel, voltage-dependent, beta 1 subunit
  • domestic cat(101089057) calcium channel, voltage-dependent, beta 1 subunit
  • domestic guinea pig(100721141) calcium channel, voltage-dependent, beta 1 subunit
  • naked mole-rat(101714578) calcium channel, voltage-dependent, beta 1 subunit
  • dog(491030) calcium channel, voltage-dependent, beta 1 subunit

Custom & Knockdown Gene Products

Small Molecule - Allosteric Modulator

Product Number
Description
Species
Gabapentin, United States Pharmacopeia (USP) Reference Standard,
Species
human
Pregabalin, European Pharmacopoeia (EP) Reference Standard,
Species
human
Gabapentin, European Pharmacopoeia (EP) Reference Standard,
Species
human
Gabapentin solution, 10 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Gabapentin solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CACNB1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-Calcium Channel (β1 subunit) antibody produced in rabbit, ~1 mg/mL, fractionated antiserum, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
western blot

Small Molecule - Blocker

Product Number
Description
Species
Bepridil hydrochloride, powder,
Species
human
Terodiline hydrochloride, ≥98% (HPLC), solid,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CACNB1,
Species
human
MISSION® esiRNA, targeting mouse Cacnb1,
Species
mouse