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Showing 1-30 of 36 results for "a2862" within Papers
O Mezghrani et al.
Die Pharmazie, 66(10), 754-760 (2011-10-27)
The main purpose of this research work was to design an optimized self micro-emulsifying drug delivery system (SMEDDS) to enhance the bioavailability of the poor water soluble drug, astilbin. The solubility of astilbin was evaluated in various vehicles. Pseudoternary phase
Jingqun Huang et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 49(9), 1943-1947 (2011-05-24)
Flavonoids are widely found in plants and many of them possess biological and pharmacological activities. In the present study, we assessed the effects of the flavonoids Genistein, Apigenin, Quercetin, Rutin and Astilbin on xanthine oxidase (XO) activities in vitro, and
Rui-zhi Zhao et al.
Pakistan journal of pharmaceutical sciences, 26(1), 1-6 (2012-12-25)
Sarcandra glaber is a common traditional Chinese medicine used to treat psoriasis and other infectious diseases, isofraxidin and astilbin are the main components of it. In order to study the pharmacokinetics of Sarcandra glabra, an HPLC method for simultaneous determination
Xi-Cheng He et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(23), 3595-3598 (2013-03-13)
Astilbin in 28 Smilax glabra (red and white cross-section) from different sources was determined by HPLC. Pharmacodynamics and component of S. glabra was investigated through inflammation experiment (penetration type). The analysis was performed on a Hypersil ODS2 column (4.6 mm
Y Cai et al.
Inflammation research : official journal of the European Histamine Research Society ... [et al.], 52(8), 334-340 (2003-09-25)
To examine the therapeutic effects of astilbin, a flavanoid isolated from Rhizoma Smilacis Glabrae, on arthritis and to compare it with cyclosporine A (CsA). Type II collagen-induced arthritis in mice and its in vitro assays for proliferation, matrix metalloproteinase (MMP)
Xiao-dan Wang et al.
International journal of pharmaceutics, 378(1-2), 1-8 (2009-05-26)
This study was designed to understand the transport profiles of astilbin and taxifolin in Caco-2 cell model and their effects on the function and expression of P-glycoprotein. The transport studies were examined using Caco-2 cells cultured on Transwell inserts. Their
Ping Li et al.
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 32(2), 181-185 (2012-04-25)
This study examined the effect of astilbin on the proliferation of rat aortic smooth muscle cells (RASMCs) induced by angiotensin II (AngII) and explored the possible mechanisms. Cell proliferation model of RASMCs was induced by treatmente with AngII. Cells were
Antioxidant activity of Rhizoma Smilacis Glabrae extracts and its key constituent-astilbin
Zhang QF, et al.,
Food Chemistry, 115(1), 297-303 (2009)
Rong-Kai Lin et al.
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 18(6), 463-466 (2010-07-01)
To investigate the effects of astilbin on the expressions of TNF alpha and IL-10 during liver warm ischemia-reperfusion injury. C57BL/ 6 mice were randomly divided into 4 groups (n = 8): sham-operated group (Sham), model control group(I/R), low dosage of
Yinjie Wang et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(12), 1859-1861 (2012-09-25)
To establish a SPE-HPLC method for analyzing astilbin in rats serum and explore the effects of Yinxieling (YXL) prescription and Smilacis Glabrae Rhizoma on the pharmacokinetic characteristics of effective components. Male Sprague-dawley rats were administrated YXL and Smilacis Glabrae Rhizoma
Qing-Feng Zhang et al.
Natural product research, 27(3), 277-281 (2012-03-10)
Rhizoma Smilacis Glabrae (RSG) and Rhizoma Smilacis Chinae (RSC) are two herbal materials that belong to the same genera and are both listed in the Chinese Pharmacopoeia. Chemical constituents in the two species were compared by HPLC-DAD-MS/MS. Many common constituents
Gui-Sheng Li et al.
Planta medica, 75(14), 1470-1475 (2009-08-01)
Astilbin, a flavonoid compound, was isolated from the rhizome of Smilax glabra Roxb. This study was conducted to investigate the efficacy of astilbin on experimental diabetic nephropathy (DN) in vivo and in vitro and its possible mechanisms. Astilbin was added
Guoyan Liang et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 59, 152772-152772 (2019-04-22)
Rhizoma smilacis glabrae (RSG, tufuling) has been widely used in traditional Chinese medicine for deoxidation, dampness relief, and easing joint movement. The chemical composition of RSG has been systematically confirmed, and some of its compounds have been revealed to possess
Mingjian Fei et al.
The Journal of allergy and clinical immunology, 116(6), 1350-1356 (2005-12-13)
IL-10 is known as a negative regulator for inflammatory diseases, including contact dermatitis. However, only a few drug candidates are reported to induce endogenous IL-10. We sought to elucidate a new mechanism underlying the immunosuppressive properties of astilbin through negative
Haiqiu Huang et al.
Journal of agricultural and food chemistry, 59(9), 4562-4569 (2011-04-12)
Engeletin, a flavonoid compound, was isolated from the leaves of Engelhardia roxburghiana for the first time, along with astilbin, another flavonoid. The chemical structures of engeletin and astilbin were confirmed by (1)H and (13)C nuclear magnetic resonance (NMR) and mass
Chao Wang et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 35(6), 714-717 (2010-06-16)
To study the chemical constituents of the plant of Sarcandra glabra and provide reference for the study of the bioactive substances. The compounds were isolated from the EtOH extract by various chromatographic methods and their structures were elucidated by their
Qing-Feng Zhang et al.
Journal of natural medicines, 67(1), 207-211 (2012-03-03)
Rhizoma Smilacis Glabrae (RSG) is a commonly used herbal material in functional food and Traditional Chinese Medicine. A HPLC chromatographic fingerprint was developed for its quality control and species differentiation. Nine peaks were found in the chromatogram of RSG and
Nicolas Landrault et al.
Journal of agricultural and food chemistry, 50(7), 2046-2052 (2002-03-21)
Phenolics from grapes and wines can play a role against oxidation and development of atherosclerosis. Stilbenes have been shown to have cancer chemopreventive activity and to protect lipoproteins from oxidative damage. A method for the direct determination of stilbene oligomers
Shao-Hua Song et al.
Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, 7(8), 753-757 (2009-08-13)
To investigate the protective effects of astilbin on renal ischemia-reperfusion (IR) injury in rats. Twenty-four male SD rats, two months old, were randomly allocated into three groups: sham-operated group (n=8), untreated group (n=8) and astilbin group (n=8). Rats in the
S Zou et al.
Transplantation proceedings, 42(9), 3798-3802 (2010-11-26)
The effect of astilbin on acute graft rejection was investigated in C57BL/6 mice carrying BALB/c hearts heterotopically transplanted into the neck vessels. Daily treatment with astilbin (50, 125, or 250 mg/kg intraperitoneally) significantly prolonged the survival of grafts in a
H Haraguchi et al.
Bioscience, biotechnology, and biochemistry, 61(4), 651-654 (1997-04-01)
Dihydroflavonol taxifolin and its glycoside, astilbin, from Engelhardtia chrysolepis inhibited rat lens and recombinant human aldose reductase. Taxifolin also inhibited sorbitol accumulation in human red blood cells. Furthermore, this dihydroflavonol aglycone maintained the clarity of rat lens incubated with a
Yong-Jiang Xu et al.
Planta medica, 77(11), 1139-1148 (2011-02-18)
The extracts of two medicinal plants used in traditionalmedicine against malariawere characterized by means of an LC‑SPE‑NMR and LC‑MS platform. The structure of a series of major constituents from Bafodeya benna, as well as minor constituents from Ormocarpum kirkii, was
Xiao-Ya Shang et al.
Journal of Asian natural products research, 14(10), 966-972 (2012-10-11)
A new dihydroflavonol glycoside dimer 6,6-bisastilbin (1) and a new nitrile-containing metabolite (Z)-5α,6β-dihydroxy-4β-methoxy-2-cyclohexene-Δ(1,α)-acetonitrile (2), together with three known analogs, bauhinin, bauhinilide, and dehydrodicatechin A, have been isolated from an ethanol extract of Bauhinia aurea. Their structures were determined by spectroscopic
Luciane G Batista Pereira et al.
Pest management science, 58(5), 503-507 (2002-05-10)
Astilbin was isolated in high yield from Dimorphandra mollis, and its insecticidal and growth inhibiting activity by stomach ingestion were evaluated against Anticarsia gemmatalis and Spodoptera frugiperda. The insecticidal activity of astilbin, the weight reduction of the larval phase and
Yanbing Ding et al.
Biochemical and biophysical research communications, 446(2), 529-534 (2014-03-13)
Astilbin, a major bioactive compound from Rhizoma smilacis glabrae, has been reported to possess anti-inflammatory properties. Our study first evaluated astilbin on dextran sulfate sodium (DSS)-induced acute colitis in mice. By intraperitoneal injection of astilbin, the severity of colitis was
Jinping Zhao et al.
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 29(2), 212-214 (2009-04-29)
The inhibitory effect of astilbin on transplant arteriosclerosis in murine model of thoracic aorta transplantation was examined. Model of rat thoracic aorta transplantation was established. Ninety rats were divided into three groups. In isograft group, the thoracic aorta of Brown
Shao-hua Song et al.
Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, 8(2), 145-151 (2010-02-10)
To explore the effects of astilbin on the maturation and immunologic function of mouse bone marrow-derived dendritic cells (DCs). Mouse bone marrow cells were cultured with recombinant mouse granulocyte-macrophage colony-stimulating factor and interleukin-4 (IL-4) for 5 days to get immature
Xu-hong Yang et al.
Yao xue xue bao = Acta pharmaceutica Sinica, 43(9), 974-978 (2008-12-04)
Ten compounds were isolated from the leaves of Rhizophora stylosa, one kind of mangrove plants distributed in the tropical and subtropical areas of the world. Their structures were identified as taraxerone (1), taraxerol (2), beta-sitosterol (3), careaborin (4), cis-careaborin (5)
Lvyi Chen et al.
Planta medica, 77(16), 1769-1773 (2011-05-27)
Astilbin is a flavonoid compound isolated from the rhizome of Smilax china L. The effects and possible mechanisms of astilbin on hyperuricemia and nephropathy rats were elucidated in this study. Different dosages of astilbin (1.25, 2.5, and 5.0 mg/kg) were
Xin-Rong Wu et al.
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 32(10), 1606-1609 (2010-02-02)
To investigate the process of separating and purifying total flavonoids from Smilax glabra. With the contents of total flavonoids, astilbin and engelitin as indices, the optimum process of separating and purifying flavonoids from Smilax glabra was screened by static and
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