Merck
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180947

Sigma-Aldrich

Alginic acid sodium salt

powder

Synonym(s):
Algin, Sodium alginate
CAS Number:
MDL number:

Quality Level

biological source

algae (marine)

form

powder

viscosity

15-25 cP, 1 % in H2O

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General description

Alginic acid sodium is a gelling and nontoxic anionic polysaccharide. The carboxylic acid groups on the alginic acid chain, renders it insoluble in water.However, converting alginic acid to its sodium form, enables it to solubilize in water easily.

Application

Alginic acid sodium is used:
  • in combination with chitosan, to fabricate a biodegradable porous scaffold for bone tissue engineering.
  • to study the characteristics of a modified amphiphilic alginate derivative
  • to the study the impact of alginate on the rate of lipid digestion by employing an in vitro digestion model
  • in the preparation of alginate hydrogels
  • as encapsulating agents of microparticles of β-galactosidae

Packaging

100, 250, 500 g in poly bottle

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

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  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. How do I dissolve Product No. 180947, Alginic acid sodium salt?

    Product No. 180947, Alginic acid sodium salt, is soluble in water.  

  6. What is the molecular weight of Product No. 180947, Alginic acid sodium salt?

    The molecular weight of Product No. 180947, Alginic acid sodium salt, is 120,000-190,000 g/moL.

  7. What is the ratio of mannuronic acid to guluronic acid in Product No. 180947, Alginic acid sodium salt?

    The ratio of mannuronic acid to guluronic acid (M/G ratio) is 1.56.

  8. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Role of calcium and calcium-binding agents on the lipase digestibility of emulsified lipids using an in vitro digestion model
Hu M, et al.
Food Hydrocolloids, 24(8), 719-725 (2010)
Zhensheng Li et al.
Biomaterials, 26(18), 3919-3928 (2005-01-01)
A biodegradable scaffold in tissue engineering serves as a temporary skeleton to accommodate and stimulate new tissue growth. Here we report on the development of a biodegradable porous scaffold made from naturally derived chitosan and alginate polymers with significantly improved
Thao Thi Thu Vu et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 100(7), 1980-1988 (2012-08-14)
Alginate hydrogels possess tunable mechanical properties that can mimic soft marrow tissue and present three-dimensional (3D) cues. This study evaluates its utility for supporting leukemic cell growth in vitro and its impact on cell survival, growth, and differentiation. Our results
Microencapsulation of ?-galactosidase with different biopolymers by a spray-drying process
Estevinho BN, et al.
Food Research International, 64, 134-140 (2014)
Nora Bloise et al.
Frontiers in bioengineering and biotechnology, 8, 292-292 (2020-04-23)
Coronary artery disease is a severe ischemic condition characterized by the reduction of blood flow in the arteries of the heart that results in the dysfunction and death of cardiac tissue. Despite research over several decades on how to reduce

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