23100

Chloral hydrate

crystallized, ≥98.0% (T)

• Synonym(s): Trichloroacetaldehyde hydrate
• Linear Formula: Cl₃CCH(OH)₂
• CAS Number: 302-17-0
• Molecular Weight: 165.40
• Beilstein: 1698497
• EC Number: 206-117-5
• MDL number: MFCD00044479
• PubChem Substance ID: 57648021
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: ≥98.0% (T)
• form: solid
• quality: crystallized
• mp: 57 °C (lit.)
• SMILES string: OC(O)C(Cl)(Cl)Cl
• InChI: 1S/C2H3Cl3O2/c3-2(4,5)1(6)7/h1,6-7H
• InChI key: RNFNDJAIBTYOQL-UHFFFAOYSA-N

Description

Application

Chloral hydrate can be used as:

• A reactant in the asymmetric synthesis of β-trichloromethyl-β-hydroxyketones by reacting with chiral imines.
• A water carrier for the efficient deprotectionof acetals, dithioacetals, and tetrahydropyranyl ethers in organic solvents.
• A reactant to synthesize 2-(hydroxyimino)-N-(2-iodophenyl)acetamide using 2-iodoaniline in the presence of hydrochloric acid, sodium sulfate, and hydroxyamine hydrochloride.

Other Notes

Sales restrictions may apply

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Statements: H301 - H315 - H319
• Precautionary Statements: P264 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338 - P332 + P313
• Hazard Classifications: Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2
• Storage Class Code: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves