All Photos(1)

295590

Sigma-Aldrich

Nitrous oxide

99%

Synonym(s):
Dinitrogen monoxide, Laughing gas
Empirical Formula (Hill Notation):
N2O
CAS Number:
Molecular Weight:
44.01
Beilstein:
8137358
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

vapor density

1.53 (15 °C, vs air)

vapor pressure

51.7 mmHg ( 21 °C)

assay

99%

bp

−88 °C (lit.)

mp

−91 °C (lit.)

SMILES string

[O-][N+]#N

InChI

1S/N2O/c1-2-3

InChI key

GQPLMRYTRLFLPF-UHFFFAOYSA-N

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Application

  • Nitrous oxide allows selective oxygen atom transfer reactions while minimizing the risk of over-oxidation. Therefore, it is used to oxidize disilenes, silanimines, silaethenes and silylenes.
  • Along with Ru-porphyrin catalyst, it can be used in the epoxidation of olefins and steroids.
  • It can be used as an oxidant in for the metal-catalyzed oxidative homo- and cross-coupling of Grignard reagents.
  • N2O can also be used as a nitrogen-dopant source to synthesize p-type zinc oxide nanowires (ZnO NWs) via vapor-liquid-solid growth.

Packaging

227 g in steel cylinder

Other Notes

For 295590-270G-EU packaging: 400 mL of aluminium cylinder equipped with brass valve.

Recommended products

  • For 295590-270G-EU: outlet fitting is DIN 477-1 no. 1, Z742160 or Z742161 are the recommended regulators.
  • For 295590-227G: Z146706 CGA 180 Regulator OR Z146943 CGA 110 valve with Z147095 CGA 110 to CGA 180 adapter and Z146986 washer for valve.

Pictograms

Flame over circleGas cylinder

Signal Word

Danger

Hazard Statements

Precautionary Statements

Hazard Classifications

Ox. Gas 1 - Press. Gas Liquefied gas

Storage Class Code

2A - Gases

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Git Lidman et al.
Developmental medicine and child neurology, 57(8), 754-761 (2015-03-27)
To investigate the effects of repeated botulinum toxin A (BoNT-A) injections combined with occupational therapy, including a splint, compared with occupational therapy alone on hand function in children with unilateral spastic cerebral palsy (USCP), in all International Classification of Functioning...
Synthetic chemistry with nitrous oxide.
Severin K.
Chemical Society Reviews, 44(17), 6375-6386 (2015)
Nitrous oxide oxidation of olefins catalyzed by ruthenium porphyrin complexes.
Yamada T, et al.
Chemistry Letters (Jpn), 30(3), 268-269 (2001)
R L M Schils et al.
Animal : an international journal of animal bioscience, 7 Suppl 1, 29-40 (2012-10-04)
Herbivores are a significant source of nitrous oxide (N(2)O) emissions. They account for a large share of manure-related N(2)O emissions, as well as soil-related N(2)O emissions through the use of grazing land, and land for feed and forage production. It...
Oxidative Coupling Reactions of Grignard Reagents with Nitrous Oxide.
Kiefer G, et al.
Angewandte Chemie (International Edition in English), 52(24), 6302-6305 (2013)

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